Pyronaridine tetraphosphate
Pyronaridine tetraphosphate (CAS: 76748-86-2), with the empirical formula C29H32ClN5O2·4H3PO4 and a molecular weight of 910.03, is a chemical compound primarily known for its role as an antimalarial agent. It functions as an antiparasitic and antiprotozoal agent, targeting specific parasitic infections. Supplied by Tech Serve Solutions, this compound is typically provided at a high purity for research and development purposes in the fields of medicinal chemistry and pharmacology.
- IUPAC
- 2-Methoxy-7-chloro-10[3′,5′-bis(pyrrolidinyl-1-methyl-)4′-hydroxyphenyl]aminobenzyl-(b)-1,5-naphthyridine tetraphosphate

Antimalarial Research
Pyronaridine tetraphosphate is investigated for its efficacy against malaria parasites, particularly Plasmodium falciparum. Its mechanism of action involves interfering with the parasite's heme detoxification pathway.
Antiparasitic Agent
Beyond malaria, this compound is studied for broader antiparasitic and antiprotozoal activities. Its chemical structure lends itself to research into treatments for various protozoal infections.
Medicinal Chemistry
Researchers in medicinal chemistry utilise Pyronaridine tetraphosphate as a reference compound or a starting point for developing novel therapeutic agents. Its properties make it valuable in structure-activity relationship studies.
| Molecular weight | 910.03 |
|---|---|
| Empirical formula | C29H32ClN5O2·4H3PO4 |
| Assay | ≥95% (HPLC) |
| Storage temperature | 2-8°C |



Hazard statements
- H301Toxic if swallowed
- H318Causes serious eye damage
- H361Suspected of damaging fertility or the unborn child
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 63-22-41 |
| Safety statements (S) | 26-36/37-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pyronaridine tetraphosphate used for?
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Pyronaridine tetraphosphate is primarily used as an antimalarial agent and is investigated for broader antiparasitic and antiprotozoal activities. It is also utilized in medicinal chemistry research.
What is the CAS number and formula for Pyronaridine tetraphosphate?
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The CAS number for Pyronaridine tetraphosphate is 76748-86-2, and its empirical formula is C29H32ClN5O2·4H3PO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Pyronaridine tetraphosphate with an assay of ≥95% by HPLC. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should Pyronaridine tetraphosphate be handled and stored?
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Due to its hazards (H301-H318-H361-H413), handle with appropriate personal protective equipment including a dust mask (N95), eyeshields, face shields, and gloves. Store at 2-8°C. This chemical is classified with GHS05, GHS06, GHS08 symbols and a Danger signal word.
Is Pyronaridine tetraphosphate exported by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Pyronaridine tetraphosphate.
How can I request a quote or sample?
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To request a quote or sample of Pyronaridine tetraphosphate, please contact our sales department through the website or by phone.
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