Protriptyline hydrochloride
Protriptyline hydrochloride (CAS 1225-55-4), with the molecular formula C19H21N · HCl and a molecular weight of 299.84 g/mol, is a white to off-white powder. It functions as a biogenic amine transport inhibitor, making it valuable in neuroscience research. This compound is utilized in studies investigating cell signaling, neurotransmission, and obesity. Supplied by TSS, it meets high purity standards for research applications.

Neuroscience Research
Protriptyline hydrochloride serves as a tool in neuroscience for studying neurotransmitter reuptake mechanisms, particularly involving norepinephrine and serotonin. It aids in understanding the pathways involved in mood regulation and neuronal communication.
Biochemical Assays
This compound is used in biochemical assays to investigate the function of biogenic amine transporters. Its inhibitory properties allow researchers to explore the dynamics of neurotransmission and related cellular processes.
Obesity Research Studies
Research into obesity can involve the use of protriptyline hydrochloride to study the role of neurotransmission in appetite control and energy balance. It helps in modelling and understanding the complex factors contributing to obesity.
GPCR Modulation Studies
As a modulator of GPCRs, protriptyline hydrochloride is employed in studies focusing on G protein-coupled receptor signaling pathways. This is relevant for understanding various physiological and pathological processes.
| Molecular weight | 299.84 |
|---|---|
| Empirical formula | C19H21N · HCl |
| Assay | ≥99% (TLC) |
| Form | powder |
| Colour | white to off-white |
| Solubility | H2O: soluble50 mg/mL |

Hazard statements
- H301Toxic if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Protriptyline hydrochloride used for?
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Protriptyline hydrochloride is used in neuroscience research for studying biogenic amine transport, neurotransmission, and its potential role in obesity research. It also serves as a tool in GPCR modulation studies.
What is the CAS number and formula for Protriptyline hydrochloride?
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The CAS number for Protriptyline hydrochloride is 1225-55-4, and its empirical formula is C19H21N · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Protriptyline hydrochloride with an assay of ≥99% by TLC. We do not represent this product as USP, BP, or EP grade.
How should Protriptyline hydrochloride be handled safely?
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Protriptyline hydrochloride is classified as Dangerous. Handle with appropriate personal protective equipment including a dust mask (N95 US), eyeshields, faceshields, and gloves. Avoid inhalation of dust and contact with skin and eyes. Refer to the Safety Data Sheet for full details.
Is Protriptyline hydrochloride a controlled substance?
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The provided data does not indicate that Protriptyline hydrochloride is a controlled substance.
How is Protriptyline hydrochloride packed and shipped?
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Protriptyline hydrochloride is packed according to international shipping regulations for hazardous materials, including UN 2811 classification. TSS exports globally.
How can I request a sample or quote for Protriptyline hydrochloride?
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To request a sample or a quote for Protriptyline hydrochloride, please use the contact form on our website or reach out to our sales department directly.
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