Protoporphyrin IX
Protoporphyrin IX (CAS: 553-12-8, C34H34N4O4, MW: 562.66) is a key heme precursor vital in biological systems. This bioactive small molecule is recognised for its role in activating soluble guanylyl cyclase. Supplied by Tech Serve Solutions with an assay of ≥95%, it is suitable for research applications in cell biology, biochemistry, and neuroscience, contributing to studies on oxidation-reduction processes and cellular signaling.
- IUPAC
- 3,7,12,17-Tetramethyl-8,13-divinyl-2,18-porphinedipropionic acid,Kammerer’s porphyrin,Ooporphyrin
- Synonyms
- 3,7,12,17-Tetramethyl-8,13-divinyl-2,18-porphinedipropionic acidKammerer’s porphyrinOoporphyrin

Guanylyl Cyclase Activation
Protoporphyrin IX acts as an activator for soluble guanylyl cyclase, an enzyme crucial in intracellular signaling pathways. This activation leads to the production of cyclic guanosine monophosphate (cGMP).
Biochemical Research
As a fundamental molecule in heme biosynthesis, Protoporphyrin IX is used in research to study metabolic pathways, enzyme kinetics, and cellular processes. Its properties are relevant in fields such as cell biology and neuroscience.
Oxidation-Reduction Studies
The porphyrin structure of Protoporphyrin IX allows it to participate in oxidation-reduction reactions. This makes it a valuable reagent for investigating electron transfer mechanisms and related biological processes.
| Molecular weight | 562.66 |
|---|---|
| Empirical formula | C34H34N4O4 |
| Assay | ≥95% |
| Storage temperature | 2-8°C |
| Application | Activates soluble guanylyl cyclase. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 402 nm; λem 625 nm (bound to HRP)λex 409 nm; λem 633 nm |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Protoporphyrin IX used for?
+
Protoporphyrin IX is used to activate soluble guanylyl cyclase and in biochemical research related to heme biosynthesis, cellular signaling, and oxidation-reduction processes.
What is the CAS number and chemical formula for Protoporphyrin IX?
+
The CAS number for Protoporphyrin IX is 553-12-8, and its empirical formula is C34H34N4O4.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Protoporphyrin IX with a purity of ≥95%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should Protoporphyrin IX be handled safely?
+
Handle Protoporphyrin IX with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation, as it may cause skin irritation, eye irritation, and respiratory irritation (H315-H319-H335).
Is Protoporphyrin IX available for export?
+
Yes, Tech Serve Solutions specialises in global supply and export of fine chemicals. Please contact us for export availability and shipping details.
How can I request a sample or quote for Protoporphyrin IX?
+
To request a sample or a quotation for Protoporphyrin IX, please contact our sales department through the website or by telephone.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents

(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis