Propargylamine
Propargylamine (CAS 2450-71-7), with the chemical formula HC≡CCH2NH2, is a terminal alkyne and a primary amine. This volatile, flammable liquid has a molecular weight of 55.08 g/mol. It serves as a valuable building block in organic synthesis, particularly for introducing the propargyl group into molecules. Its reactivity makes it useful in creating diverse chemical structures for research and development purposes.
- IUPAC
- 2-Propynylamine,3-Amino-1-propyne
- Synonyms
- 2-Propynylamine3-Amino-1-propyne
Organic Synthesis Intermediate
Propargylamine is a key intermediate in the synthesis of more complex organic molecules. Its dual functionality, featuring both a terminal alkyne and a primary amine, allows for a wide range of chemical transformations.
Pharmaceutical Research
It is employed as a building block in the development of novel pharmaceutical compounds. The propargyl moiety can be incorporated into drug candidates to modulate their properties or to facilitate further synthetic elaborations.
Material Science
The reactive alkyne group can participate in polymerization reactions or click chemistry, making propargylamine a useful component in the synthesis of specialised polymers and functional materials.
Agrochemical Development
Propargylamine can be utilised in the synthesis pathways for new agrochemical active ingredients, contributing to the development of crop protection agents.
| Molecular weight | 55.08 |
|---|---|
| Linear formula | HC≡CCH2NH2 |
| Assay | 98% |
| Boiling point | 83 °C(lit.) |
| Density | 0.86 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.449(lit.) |
| Storage temperature | 2-8°C |
| Contains / stabiliser | ≤2.5% water |
Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H310Fatal in contact with skin
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P302IF ON SKIN
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 6 °C / 42.8 °F |
| Transport (UN / ADR) | UN 1992 3/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,T |
| Risk statements (R) | 11-22-24-34 |
| Safety statements (S) | 16-26-33-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Propargylamine used for?
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Propargylamine (CAS 2450-71-7) is primarily used as a versatile building block in organic synthesis for the creation of complex molecules, including potential pharmaceutical and agrochemical compounds, as well as in material science applications.
What are the CAS number and chemical formula for Propargylamine?
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The CAS number for Propargylamine is 2450-71-7 and its chemical formula is HC≡CCH2NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Propargylamine with an assay of 98%. We do not represent this product as meeting USP, BP, or EP pharmacopoeial standards.
How should Propargylamine be handled safely?
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Propargylamine is highly flammable and toxic. It causes severe skin burns and eye damage. Handle with extreme caution in a well-ventilated area, wearing appropriate personal protective equipment including gloves, goggles, a faceshield, and a suitable respirator. Keep away from heat, sparks, and open flames. Refer to the Safety Data Sheet for comprehensive handling guidelines.
Is Propargylamine a controlled substance?
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The provided data does not indicate that Propargylamine is a controlled substance. Always comply with local regulations regarding its handling and use.
How is Propargylamine packed, shipped, and exported?
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Propargylamine is carefully packed according to international shipping regulations for hazardous materials. TSS is experienced in exporting chemicals globally, ensuring compliance with all necessary documentation and transport requirements.
How can I request a quote or sample of Propargylamine?
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To request a quote or a sample of Propargylamine, please contact our sales team through the website or via the provided contact details. Our team will be pleased to assist you.
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