Propargylamine hydrochloride
Propargylamine hydrochloride (CAS: 15430-52-1), with the chemical formula HC≡CCH₂NH₂ · HCl and a molecular weight of 91.54 g/mol, is a vital organic building block. This compound features a terminal alkyne and a primary amine, making it a versatile reagent in chemical synthesis and bioconjugation. It is frequently employed in the development of novel molecules and functionalized materials.
- IUPAC
- 2-Propynylamine hydrochloride,3-Amino-1-propyne hydrochloride
- Synonyms
- 2-Propynylamine hydrochloride3-Amino-1-propyne hydrochloride

Organic Synthesis Intermediate
Propargylamine hydrochloride serves as a key intermediate in the synthesis of various complex organic molecules. Its bifunctional nature allows for diverse chemical transformations, including click chemistry reactions and the introduction of amine and alkyne functionalities.
Bioconjugation Chemistry
This compound is valuable in bioconjugation, particularly for linking biomolecules via reactions involving its terminal alkyne group. It is utilized in creating probes, modifying peptides, and developing targeted drug delivery systems.
Material Science
The unique structure of propargylamine hydrochloride lends itself to the development of functional polymers and advanced materials. It can be incorporated into polymer backbones or used to functionalize surfaces for specific applications.
| Molecular weight | 91.54 |
|---|---|
| Linear formula | HC≡CCH2NH2 · HCl |
| Assay | 95% |
| Storage temperature | 2-8°C |
| Melting point | 179-182 °C(lit.) |

Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Propargylamine hydrochloride primarily used for?
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Propargylamine hydrochloride is primarily used as a versatile building block in organic synthesis, bioconjugation chemistry, and material science due to its terminal alkyne and primary amine functionalities.
What is the CAS number and chemical formula for Propargylamine hydrochloride?
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The CAS number for Propargylamine hydrochloride is 15430-52-1, and its chemical formula is HC≡CCH₂NH₂ · HCl.
What grade and purity does Tech Serve Solutions supply for Propargylamine hydrochloride?
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Tech Serve Solutions supplies Propargylamine hydrochloride with an assay of 95%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should Propargylamine hydrochloride be handled safely?
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Propargylamine hydrochloride is classified as Dangerous. It is harmful if swallowed (H301), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a type P2 respirator, is essential during handling. Store at 2-8°C.
Is Propargylamine hydrochloride a controlled substance?
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The provided data does not indicate that Propargylamine hydrochloride is a controlled substance.
How is Propargylamine hydrochloride packed and shipped?
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Propargylamine hydrochloride is packed and shipped according to relevant regulations for hazardous materials. Specific details regarding packaging for export can be provided upon request.
How can I request a quote or sample for Propargylamine hydrochloride?
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To request a quote or sample for Propargylamine hydrochloride, please contact our sales team through the website or by phone, providing your specific requirements.
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