Prednisolone 21-acetate
Prednisolone 21-acetate (CAS: 52-21-1), with the molecular formula C23H30O6 and a molecular weight of 402.48, is a synthetic corticosteroid. It is primarily employed in chemical synthesis and chiral building block applications. This compound is known for its specific optical activity and finds utility in the construction of complex molecules within advanced chemical research and development settings. Tech Serve Solutions supplies this reagent with a minimum assay of 97.0% by HPLC.
- IUPAC
- 1,4-Pregnadiene-11β,17α,21-triol-3,20-dione 21-acetate,11β,17α,21-Trihydroxy-1,4-pregnadiene-3,20-dione 21-acetate,21-Acetoxy-1,4-pregnadiene-11β,17α-diol-3,20-dione
- Synonyms
- 1,4-Pregnadiene-11β,17α,21-triol-3,20-dione 21-acetate11β,17α,21-Trihydroxy-1,4-pregnadiene-3,20-dione 21-acetate21-Acetoxy-1,4-pregnadiene-11β,17α-diol-3,20-dione

Asymmetric Synthesis
Prednisolone 21-acetate serves as a valuable chiral building block in asymmetric synthesis. Its defined stereochemistry allows for the stereoselective construction of complex molecular architectures.
Chemical Synthesis
This compound is utilised as a reagent or intermediate in various chemical synthesis pathways. It contributes to the development of novel chemical entities and materials.
Complex Molecule Construction
The unique structure of Prednisolone 21-acetate makes it suitable for the intricate synthesis of complex organic molecules, aiding researchers in advanced organic chemistry.
| Molecular weight | 402.48 |
|---|---|
| Empirical formula | C23H30O6 |
| Assay | ≥97.0% (HPLC) |
| Optical activity | [α]20/D +116±2°, c = 1% in dioxane |
| Melting point | 240-244 °C |

Hazard statements
- H300Fatal if swallowed
Precautionary statements
- P264Wash thoroughly after handling
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Prednisolone 21-acetate used for?
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Prednisolone 21-acetate is used in asymmetric synthesis, chemical synthesis, chiral building blocks, and the construction of complex molecules. It is a synthetic corticosteroid employed in chemical research.
What is the CAS number and formula for Prednisolone 21-acetate?
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The CAS number for Prednisolone 21-acetate is 52-21-1, and its empirical formula is C23H30O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Prednisolone 21-acetate with a minimum assay of ≥97.0% determined by HPLC. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade unless explicitly stated.
How should Prednisolone 21-acetate be handled?
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Prednisolone 21-acetate is classified as dangerous (GHS06, Signal Word: Danger, Hazard Statement: H300). Handle with extreme care using eyeshields, faceshields, gloves, and appropriate respiratory protection (type P2 respirator cartridges). Avoid ingestion. In case of accidental exposure, seek immediate medical attention.
Is Prednisolone 21-acetate shipped internationally?
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Yes, Tech Serve Solutions specialises in supplying and exporting fine chemicals globally. Prednisolone 21-acetate can be packed and shipped to meet international regulatory requirements.
How can I request a quote or sample for Prednisolone 21-acetate?
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To request a quote or a sample of Prednisolone 21-acetate, please contact our sales department through the website or by phone. Our team will be pleased to assist you.
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