Methoxyacetyl chloride
Methoxyacetyl chloride (CAS: 38870-89-2) with the linear formula CH₃OCH₂COCl and a molar mass of 108.52 g/mol, is a reactive acid halide. It serves as a versatile organic building block and intermediate in chemical synthesis. This compound is primarily utilised in laboratory research and the development of new chemical entities. Its applications span various areas of organic chemistry where the introduction of the methoxyacetyl group is required.
- IUPAC
- Methoxyacetic acid chloride
- Synonyms
- Methoxyacetic acid chlorideMethoxyacetyl chloride

Organic Synthesis Intermediate
Methoxyacetyl chloride is a valuable reagent for introducing the methoxyacetyl functional group in organic synthesis. It is used in the preparation of esters, amides, and other derivatives.
Pharmaceutical Research
This compound can serve as a building block in the synthesis of complex molecules with potential pharmaceutical activity. Its reactivity allows for diverse chemical transformations.
Material Science
It may find applications in the synthesis of specialised polymers or functional materials where the methoxyacetyl moiety imparts specific properties.
| Molecular weight | 108.52 |
|---|---|
| Linear formula | CH3OCH2COCl |
| Assay | 97% |
| Boiling point | 112-113 °C(lit.) |
| Density | 1.187 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.419(lit.) |
| Storage temperature | 2-8°C |



Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 35 °C / 95 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34-36/37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methoxyacetyl chloride used for?
+
Methoxyacetyl chloride is primarily used as an intermediate in organic synthesis for introducing the methoxyacetyl group into various molecules, finding applications in pharmaceutical research and material science.
What is the CAS number and chemical formula for Methoxyacetyl chloride?
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The CAS number for Methoxyacetyl chloride is 38870-89-2, and its linear chemical formula is CH₃OCH₂COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions typically supplies Methoxyacetyl chloride with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Methoxyacetyl chloride be handled safely?
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Methoxyacetyl chloride is a dangerous substance. It is flammable and corrosive, causing severe skin burns and eye damage, and may cause respiratory irritation. Always handle with appropriate personal protective equipment including face shields, gloves, goggles, and suitable respiratory protection in a well-ventilated area. Consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.
Is Methoxyacetyl chloride available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Methoxyacetyl chloride, and can facilitate international orders.
How can I request a quote or sample?
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To request a quote or sample of Methoxyacetyl chloride, please contact our sales department through the website or by phone, providing your specific requirements.
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