Prednisone
Prednisone (CAS: 53-03-2, C21H26O5) is a synthetic corticosteroid with a molecular weight of 358.43 g/mol. It is primarily utilised in chemical synthesis and as a chiral building block in the construction of complex molecules. Its specific optical activity and verified assay of 98% make it a reliable reagent for research and development applications in organic chemistry.
- IUPAC
- 1,4-Pregnadiene-17α,21-diol-3,11,20-trione,1-Cortisone,17α,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione,Dehydrocortisone
- Synonyms
- 1-Cortisone17α,21-Dihydroxy-1,4-pregnadiene-3,11,20-trioneDehydrocortisone1,4-Pregnadiene-17α,21-diol-3,11,20-trione

Chiral Building Block
Prednisone serves as a valuable chiral building block in asymmetric synthesis. Its defined stereochemistry can be leveraged to construct enantiomerically pure complex molecules, facilitating advanced organic syntheses.
Chemical Synthesis Intermediate
With its distinct functional groups and steroid backbone, Prednisone is employed as an intermediate in chemical synthesis pathways. It enables the creation of novel compounds and the modification of existing molecular structures.
Research and Development
This compound is utilised in research laboratories for exploring new synthetic methodologies and developing advanced organic compounds. Its consistent assay ensures reproducibility in experimental outcomes.
| Molecular weight | 358.43 |
|---|---|
| Empirical formula | C21H26O5 |
| Assay | 98% |
| Optical activity | [α]25/D +169°, c = 0.5 in dioxane |
| Melting point | 236-238 °C(lit.) |

Hazard statements
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P281Use personal protective equipment as required
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 63 |
| Safety statements (S) | 36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Prednisone (CAS 53-03-2) used for?
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Prednisone is used in chemical synthesis, as a chiral building block, and in the construction of complex molecules for research and development.
What are the CAS number and formula for Prednisone?
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The CAS number for Prednisone is 53-03-2 and its empirical formula is C21H26O5.
What grade and purity does Tech Serve Solutions supply for Prednisone?
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Tech Serve Solutions supplies Prednisone with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Prednisone be handled safely?
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Prednisone is classified with GHS08 symbol and 'Warning' signal word, with hazard statement H361, indicating potential reproductive harm. Appropriate personal protective equipment includes eyeshields, gloves, and a suitable respirator (e.g., N100 or P3). Follow safety statement P281 (Use personal protective equipment as required).
Is Prednisone a controlled substance?
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Information regarding controlled substance status is not provided in the available data. Users should consult relevant local regulations.
How is Prednisone packed and shipped?
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Prednisone is packed and shipped in compliance with international shipping regulations for chemicals. Specific packaging details can be provided upon request.
How can I request a quote or sample of Prednisone?
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To request a quote or sample of Prednisone, please contact the Tech Serve Solutions sales team through our website or by phone.
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