Potassium 1-Boc-1H-indole-2-trifluoroborate
Potassium 1-Boc-1H-indole-2-trifluoroborate (CAS: 945493-51-6) is an organoboron compound with the molecular formula C13H14BF3KNO2 and a molecular weight of 323.16 g/mol. This indole derivative, featuring a trifluoroborate group, serves as a valuable building block in organic synthesis, particularly for the construction of complex molecules through cross-coupling reactions. Its structure facilitates controlled functionalization in pharmaceutical and materials science research.
- IUPAC
- Potassium 1-(tert-butoxycarbonyl)-1H-indole-2-trifluoroborate
Organic Synthesis Reagent
Utilised in cross-coupling reactions such as Suzuki-Miyaura couplings to introduce the 1-Boc-1H-indol-2-yl moiety into various organic frameworks. This enables the synthesis of complex pharmaceutical intermediates and novel organic materials.
Medicinal Chemistry Research
Serves as a key intermediate for developing new drug candidates. The indole core is prevalent in many biologically active compounds, and trifluoroborate salts offer improved stability and handling compared to boronic acids.
Materials Science
Can be employed in the synthesis of organic electronic materials or functional polymers where the indole unit can impart specific electronic or photophysical properties.
| Molecular weight | 323.16 |
|---|---|
| Empirical formula | C13H14BF3KNO2 |
| Melting point | 168-175 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H332Harmful if inhaled
| Water hazard class (WGK, DE) | 1 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/22-38 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Potassium 1-Boc-1H-indole-2-trifluoroborate used for?
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It is primarily used as a reagent in organic synthesis, particularly in cross-coupling reactions for introducing the 1-Boc-1H-indol-2-yl group. It finds applications in medicinal chemistry research and materials science.
What are the CAS number and formula for this compound?
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The CAS number is 945493-51-6, and the empirical formula (Hill notation) is C13H14BF3KNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific assay or purity will be detailed on the Certificate of Analysis provided with your order. We do not represent this product as USP, BP, or EP grade.
What are the primary safety concerns when handling this chemical?
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This compound is classified as a GHS07 irritant, with a Warning signal word. It is harmful if swallowed (H302), causes skin irritation (H315), and is harmful if inhaled (H332). Appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, should be used, and handling should occur in a well-ventilated area.
Is this chemical a controlled substance?
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The provided data does not indicate that this chemical is a controlled substance.
How is this product packed, shipped, and exported?
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Tech Serve Solutions adheres to all relevant national and international regulations for the packaging, shipping, and exporting of chemicals, ensuring safe and compliant delivery.
How can I request a sample or a quote for Potassium 1-Boc-1H-indole-2-trifluoroborate?
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To request a sample or a quote, please contact our sales department through the website or by phone, providing your contact details and the required quantity.
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