Poloxin

CAS 321688-88-4C18H19NO3Cell Biology

Poloxin (CAS: 321688-88-4), with the molecular formula C18H19NO3 and a molecular weight of 297.35 g/mol, is a chemical compound supplied by Tech Serve Solutions. Available as a white to beige powder, it is primarily utilised in cell biology research, specifically within cell signalling, neuroscience, and kinase/phosphatase biology. Poloxin serves as an inhibitor in Polo-like Kinases (PLK) and serine/threonine kinase pathways, making it a valuable reagent for biochemical studies.

IUPAC: 2-Methyl-5-(1-methylethyl)-1-[O-(2-methylbenzoyl)oxime]-2,5-Cyclohexadiene-1,4-dione

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Poloxin (C18H19NO3) — chemical structure, CAS 321688-88-4; Life Science, fine chemical supplied by Tech Serve Solutions

Cell BiologyKinase/Phosphatase BiologyPolo-like Kinases (PLK)

01 /Applications

Cell Signaling Research

Poloxin is employed as a selective inhibitor in studies investigating cell signalling pathways, particularly those involving Polo-like Kinases (PLK).

Neuroscience Studies

This compound finds application in neuroscience research to explore the role of specific kinase pathways in neuronal function and dysfunction.

Kinase/Phosphatase Biology

As a serine/threonine kinase inhibitor, Poloxin is a key tool for researchers studying the regulatory mechanisms of kinase and phosphatase activity.

02 /Properties

Molecular weight	297.35
Empirical formula	C18H19NO3
Assay	≥98% (HPLC)
Form	powder
Colour	white to beige
Solubility	DMSO: soluble5 mg/mL (clear solution, warmed)
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

GHS hazard pictogram: Environmental hazard (GHS09) — Environmental hazard

Warning

Hazard statements

H317May cause an allergic skin reaction
H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment
P280Wear protective gloves, clothing and eye/face protection

Transport (UN / ADR)	UN 3077 9 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi,N
Risk statements (R)	43-50
Safety statements (S)	36/37-61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

321688-88-4

05 /Additional specifications

Storage Condition	protect from light

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Poloxin used for?

Poloxin is used in biochemical research as an inhibitor for Polo-like Kinases (PLK) and serine/threonine kinase pathways, with applications in cell biology, cell signalling, and neuroscience.

What are the CAS number and formula for Poloxin?

The CAS number for Poloxin is 321688-88-4, and its empirical formula is C18H19NO3.

What grade and purity does Tech Serve Solutions supply for Poloxin?

Tech Serve Solutions supplies Poloxin with a purity of ≥98% (HPLC). This is a research grade chemical and is not represented as USP, BP, or EP.

How should Poloxin be handled and stored?

Poloxin is a Warning substance (GHS07, GHS09) that may cause skin irritation (H317) and is very toxic to aquatic life (H400). It should be stored at 2-8°C, protected from light, and handled with appropriate personal protective equipment.

How is Poloxin packed and shipped?

Poloxin is shipped as UN 3077, Class 9, Packing Group III, indicating it is an environmentally hazardous substance. Specific packing details are available upon request.