Plumbagin from Plumbago indica
Plumbagin (CAS: 481-42-5; Formula: C11H8O3; MW: 188.18) is a naturally occurring naphthoquinone isolated from *Plumbago indica*. This compound exhibits significant anti-proliferative properties and is recognized for its potential in cancer research and chemoprevention. It is also investigated for its role in cell biology and nutrition research. Tech Serve Solutions supplies Plumbagin for research and development purposes.
- IUPAC
- 5-Hydroxy-2-methyl-1,4-naphthoquinone
- Synonyms
- 5-Hydroxy-2-methyl-1,4-naphthoquinone
Cancer Research
Plumbagin is a subject of interest in oncology research due to its demonstrated anti-proliferative and cytotoxic effects against various cancer cell lines. Its mechanisms of action are being explored for novel therapeutic strategies.
Chemopreventive Agent Studies
The compound is studied for its potential to prevent or delay the development of cancer. Research focuses on its ability to inhibit key molecular events involved in carcinogenesis.
Cell Biology Investigations
Plumbagin serves as a valuable tool in cell biology research to investigate cellular pathways, including apoptosis induction and cell cycle regulation. Its effects on cellular processes are widely studied.
Nutrition Research
As a natural phytochemical, Plumbagin is sometimes included in studies exploring the biological activities and health impacts of plant-derived compounds.
| Molecular weight | 188.18 |
|---|---|
| Empirical formula | C11H8O3 |
| Storage temperature | −20°C |
| Melting point | 76-78 °C(lit.) |
Hazard statements
- H301Toxic if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2923 8/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-34 |
| Safety statements (S) | 22-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Plumbagin (CAS 481-42-5) used for?
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Plumbagin (CAS 481-42-5) is used in research, particularly in cancer research, chemoprevention studies, and cell biology investigations, due to its anti-proliferative properties.
What is the CAS number and molecular formula for Plumbagin?
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The CAS number for Plumbagin is 481-42-5, and its molecular formula is C11H8O3.
What grade and purity does Tech Serve Solutions supply for Plumbagin?
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Tech Serve Solutions supplies Plumbagin for research and development. Purity and grade specifications are detailed in the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
How should Plumbagin be handled and stored safely?
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Plumbagin is classified as Danger (GHS05, GHS06) and is toxic if swallowed (H301) and causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection. Store at -20°C.
Is Plumbagin exported or shipped internationally by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Plumbagin.
How can I request a quote or sample for Plumbagin?
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Please contact our sales team through the website or direct inquiry channels to request a quote or sample for Plumbagin.
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