Pizotifen
Pizotifen (CAS: 15574-96-6), a tricyclic compound with the molecular formula C19H21NS, is supplied by Tech Serve Solutions. It functions as a serotonin and histamine antagonist. Pizotifen is primarily utilised in research settings for its known therapeutic applications, including the prophylaxis of migraine and cluster headaches, and as an appetite stimulant.
- IUPAC
- Pizotifen,Pizotyline; 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine
- Synonyms
- Pizotyline4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine

Migraine Prophylaxis
Pizotifen is recognised for its efficacy in the preventative treatment of migraine and cluster headaches. Its antagonistic properties at serotonin and histamine receptors are believed to contribute to this therapeutic effect.
Appetite Stimulation
This compound has also been documented for its use as an appetite stimulant. This application is often considered in contexts where increased food intake is medically indicated.
Research Reagent
As a bioactive small molecule and approved therapeutic, Pizotifen serves as a valuable reagent in pharmacological and neuroscientific research. It is used to investigate serotonin and histamine pathways.
| Molecular weight | 295.44 |
|---|---|
| Empirical formula | C19H21NS |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Solubility | DMSO: ≥8 mg/mL |
| Storage temperature | room temp |


Hazard statements
- H302Harmful if swallowed
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P281Use personal protective equipment as required
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 63-22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pizotifen used for?
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Pizotifen is primarily used for the prophylaxis of migraine and cluster headaches, and also as an appetite stimulant. It is also employed as a research reagent in pharmacological studies.
What is the CAS number and molecular formula for Pizotifen?
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The CAS number for Pizotifen is 15574-96-6 and its molecular formula is C19H21NS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Pizotifen with an assay of ≥98% (HPLC). TSS does not represent this product as USP, BP, or EP grade.
How is Pizotifen handled and stored?
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Pizotifen is a powder that may cause irritation (H302) and is suspected of damaging fertility or the unborn child (H361). It is advised to handle with care, wearing appropriate protective equipment (P281). Store at room temperature.
How is Pizotifen packed, shipped, and exported?
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Pizotifen is carefully packed to ensure integrity during transit. Tech Serve Solutions is experienced in exporting fine chemicals globally, adhering to all relevant shipping regulations.
How can I request a sample or quote for Pizotifen?
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To request a sample or a quotation for Pizotifen, please contact our sales team through the website or by direct inquiry, providing your specific requirements and shipping details.
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