Phorbol 12,13-diacetate
Phorbol 12,13-diacetate (CAS 24928-15-2) is a bioactive small molecule with the empirical formula C24H32O8 and a molecular weight of 448.51 g/mol. This white powder is soluble in water. It is primarily utilised in research settings for its role in cell signalling and as an activator for protein kinase C (PKC) and other serine/threonine kinases. Its potent biological activity requires careful handling.
- IUPAC
- PDA
- Synonyms
- 24928-15-2PDAPhorbol 12,13-diacetate
Cell Biology Research
Used as a tool in cell biology to investigate cellular processes, pathways, and signalling mechanisms. Its ability to activate specific kinases makes it valuable for studying signal transduction.
Kinase/Phosphatase Biology Studies
This compound serves as a potent activator of Protein Kinase C (PKC) and related serine/threonine kinases. It is instrumental in research focusing on kinase function and regulation.
Neuroscience Research
Applied in neuroscience to study cellular signalling pathways relevant to neural function and potentially neurodegenerative processes, given its role in cell signalling.
| Molecular weight | 448.51 |
|---|---|
| Empirical formula | C24H32O8 |
| Form | powder |
| Colour | white |
| Solubility | H2O: soluble |
| Storage temperature | −20°C |
Hazard statements
- H300Fatal if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
- P302IF ON SKIN
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/27/28-36/37/38 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phorbol 12,13-diacetate used for?
+
Phorbol 12,13-diacetate is used in research for cell biology, cell signalling, neuroscience, and kinase/phosphatase biology. It acts as an activator for Protein Kinase C (PKC) and serine/threonine kinases.
What is the CAS number and formula for Phorbol 12,13-diacetate?
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The CAS number for Phorbol 12,13-diacetate is 24928-15-2. Its empirical formula is C24H32O8.
What grade and purity does Tech Serve Solutions supply for Phorbol 12,13-diacetate?
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Tech Serve Solutions supplies Phorbol 12,13-diacetate as a research chemical. The specific assay and purity details are available on the product's Certificate of Analysis. TSS does not represent this product as USP, BP, or EP grade.
How should Phorbol 12,13-diacetate be handled safely?
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Phorbol 12,13-diacetate is classified as Danger, with severe acute toxicity hazards (H300+H310+H330) and irritant properties (H315, H319, H335). Handling requires appropriate personal protective equipment including eyeshields, face shields, gloves, and a P2 respirator. Strict adherence to safety protocols is essential.
Is Phorbol 12,13-diacetate a controlled substance?
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The provided data does not indicate that Phorbol 12,13-diacetate is a controlled substance. However, users should always verify local regulations.
How is Phorbol 12,13-diacetate packed and shipped?
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Phorbol 12,13-diacetate is typically supplied as a powder and stored at -20°C. Shipping complies with regulations for hazardous materials, specifically UN 2811, Class 6.1, Packing Group III.
How can I request a sample or quote for Phorbol 12,13-diacetate?
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To request a sample or quote for Phorbol 12,13-diacetate, please contact Tech Serve Solutions directly through our website or sales department.
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