Ouabain octahydrate
Ouabain octahydrate (CAS: 11018-89-6), with the empirical formula C29H44O12 · 8H2O and a molecular weight of 728.77 g/mol, is a crystalline cardiac glycoside. It is known for its potent inhibitory effects on the Na+/K+-ATPase enzyme. This compound finds utility in biochemical research, particularly in studies involving ion transport, cell signaling, and cardiac physiology. Ouabain octahydrate is supplied by Tech Serve Solutions as a research-grade chemical.
- IUPAC
- 1β,3β,5β,11α,14,19-Hexahydroxycard-20(22)-enolide 3-(6-deoxy-α-L-mannopyranoside),Acocantherine,G-Strophanthin
- Synonyms
- G-StrophanthinAcocantherine1β,3β,5β,11α,14,19-Hexahydroxycard-20(22)-enolide 3-(6-deoxy-α-L-mannopyranoside)
Biochemical Research
Used as a tool compound to investigate the function and inhibition of the Na+/K+-ATPase enzyme, crucial for maintaining cellular ion gradients. It aids in studying cellular energy metabolism and signal transduction pathways.
Cardiovascular Studies
Employed in research settings to understand the mechanisms of cardiac glycosides and their effects on heart contractility and electrophysiology. Its precise action on ion pumps makes it valuable for in vitro cardiovascular research.
Neuroscience Research
Applied in studies focusing on ion channel function and neuronal signaling, given the critical role of Na+/K+-ATPase in maintaining neuronal membrane potential and function.
| Molecular weight | 728.77 |
|---|---|
| Empirical formula | C29H44O12 · 8H2O |
| Assay | ≥95% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | H2O: soluble10 mg/mL (cold)ethanol: soluble10 mg/mLH2O: soluble50 mg/mL (hot) |
| Optical activity | [α]25/D −31 to −32.5° in H2O(lit.) |
| Impurities tested | ~8 mol/mol water |
Hazard statements
- H301Toxic if swallowed
- H373May cause damage to organs through prolonged exposure
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 1544 6.1/PG 1 |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/25-33 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ATIC(471)rat ... Atp1b1(25650) |
|---|---|
| Absorption | ε1mM/220 nm, H2O 15.5 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ouabain octahydrate used for?
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Ouabain octahydrate is primarily used in biochemical and cardiovascular research for its potent inhibitory effect on the Na+/K+-ATPase enzyme, and for studying ion transport and cellular signaling.
What is the CAS number and formula for Ouabain octahydrate?
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The CAS number for Ouabain octahydrate is 11018-89-6, and its empirical formula is C29H44O12 · 8H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ouabain octahydrate with a purity of ≥95% (HPLC). This is a research-grade chemical and is not represented as USP, BP, or EP.
How should Ouabain octahydrate be handled?
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Ouabain octahydrate is highly toxic if swallowed or inhaled (H301 + H331) and may cause organ damage through prolonged exposure (H373). Handle with extreme caution in a well-ventilated area or fume hood, wearing appropriate personal protective equipment.
Is Ouabain octahydrate shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Ouabain octahydrate, which can be shipped internationally following all relevant regulations.
How can I request a quote or sample?
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To request a quote or sample for Ouabain octahydrate, please contact our sales department through the website or by phone, providing your specific requirements.
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