(+)-Nootkatone

CAS 4674-50-4C15H22OChemical Synthesis

(+)-Nootkatone (CAS: 4674-50-4, C15H22O) is a naturally occurring sesquiterpenoid ketone found in the grapefruit and is a key component of its aroma. It is also present in the bark of the Alaskan yellow cedar (Chamaecyparis nootkatensis). This compound serves as a valuable chiral building block in asymmetric synthesis and finds applications in flavour and fragrance industries, as well as in nutrition research. Its distinctive woody-grapefruit aroma makes it a sought-after ingredient.

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(+)-Nootkatone (C15H22O) — chemical structure, CAS 4674-50-4; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisCell BiologyChemical SynthesisChiral Building BlocksKetonesNutrition ResearchOrganic Building Blocks

01 /Applications

Flavour and Fragrance Industry

(+)-Nootkatone is highly valued for its intense grapefruit and woody aroma, making it a key ingredient in perfumes and flavour formulations. It contributes a natural, fresh citrus note to various consumer products.

Chemical Synthesis

As a chiral sesquiterpenoid, (+)-Nootkatone serves as a versatile building block in complex organic synthesis. Its stereochemistry is particularly useful in the creation of enantiomerically pure compounds for pharmaceutical research and development.

Nutrition Research

Naturally derived from citrus, (+)-Nootkatone is investigated for its potential health benefits. Research explores its role in metabolic studies and as a component in nutritional supplements.

Asymmetric Synthesis

The inherent chirality of (+)-Nootkatone makes it an important starting material or intermediate in asymmetric synthesis. It enables the stereoselective construction of complex molecules with defined spatial arrangements.

02 /Properties

Molecular weight	218.33
Empirical formula	C15H22O
Assay	≥99.0% (GC)
Optical activity	[α]20/D +181±3°, c = 1% in ethanol
Melting point	35-39 °C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Flash point	100 °C / 212 °F
Water hazard class (WGK, DE)	2

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

4674-50-4

MDL number

MFCD04974578

Beilstein registry

4676969

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (+)-Nootkatone used for?

(+)-Nootkatone is used in the flavour and fragrance industry for its grapefruit and woody aroma, as a chiral building block in chemical synthesis, and in nutrition research.

What are the CAS number and formula for (+)-Nootkatone?

The CAS number for (+)-Nootkatone is 4674-50-4, and its molecular formula is C15H22O.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (+)-Nootkatone with an assay of ≥99.0% (GC). We do not represent this product as USP, BP, or EP grade.

What are the safety and handling precautions for (+)-Nootkatone?

Handle (+)-Nootkatone with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The flash point is 100 °C (212 °F).

How is (+)-Nootkatone packed, shipped, and exported?

Tech Serve Solutions packs, ships, and exports (+)-Nootkatone according to international standards for chemical handling and transport. Specific packaging details are available upon request.