(+)-N-Boc-L-α-phenylglycinol

CAS 117049-14-6(CH3)3CO2CNHCH(C6H5)CH2OHChemical Synthesis

(+)-N-Boc-L-α-phenylglycinol (CAS: 117049-14-6) is a chiral amino alcohol derivative with a molecular weight of 237.29 g/mol. This compound, featuring a Boc-protected amine and a phenyl group, is a valuable building block in organic synthesis. Its specific stereochemistry makes it particularly useful in the asymmetric synthesis of complex molecules, including pharmaceutical intermediates and biologically active compounds. It is supplied with a high assay of 99% and excellent optical purity.

IUPAC: (S)-(+)-2-(Boc-amino)-2-phenylethanol
Synonyms: (S)-(+)-2-(Boc-amino)-2-phenylethanol

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(+)-N-Boc-L-α-phenylglycinol ((CH3)3CO2CNHCH(C6H5)CH2OH) — chemical structure, CAS 117049-14-6; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesAmino AlcoholsChemical BiologyChemical SynthesisPeptide Chemistry

01 /Applications

Chiral Auxiliary in Asymmetric Synthesis

(+)-N-Boc-L-α-phenylglycinol can serve as a chiral auxiliary or building block in stereoselective reactions. Its defined stereochemistry is crucial for controlling the chirality of newly formed stereocentres in target molecules.

Pharmaceutical Intermediate Synthesis

This compound is employed in the multi-step synthesis of complex pharmaceutical agents where precise stereochemical control is paramount. It contributes to the development of enantiomerically pure active pharmaceutical ingredients (APIs).

Peptide Chemistry Research

As an amino acid derivative, it finds application in specialized areas of peptide chemistry, potentially for the incorporation of non-natural amino acid motifs or for modifying peptide structures.

Chemical Biology Studies

It can be utilised in chemical biology research for the synthesis of probes or labelled molecules to investigate biological pathways and interactions.

02 /Properties

Molecular weight	237.29
Linear formula	(CH3)3CO2CNHCH(C6H5)CH2OH
Assay	99%
Optical activity	[α]19/D +37°, c = 1 in chloroform
Optical purity	ee: 99% (GLC)
Melting point	136-139 °C(lit.)

03 /Identifiers & registry

CAS number

117049-14-6

MDL number

MFCD00274206

Beilstein registry

4316842

04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is (+)-N-Boc-L-α-phenylglycinol used for?

It is primarily used as a chiral building block or auxiliary in asymmetric organic synthesis, particularly in the development of pharmaceutical intermediates and in peptide chemistry research.

What are the CAS number and formula for (+)-N-Boc-L-α-phenylglycinol?

The CAS number is 117049-14-6, and its linear formula is (CH3)3CO2CNHCH(C6H5)CH2OH.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (+)-N-Boc-L-α-phenylglycinol with an assay of 99% and high optical purity (ee: 99%). This is a research grade chemical and is not supplied as USP, BP, or EP.

How should (+)-N-Boc-L-α-phenylglycinol be handled?

According to the supplied safety data, this compound is classified under WGK 2 in Germany, indicating it is hazardous to water. Appropriate personal protective equipment should be used, and handling should occur in a well-ventilated area. Consult the Safety Data Sheet (SDS) for detailed handling procedures.

How is this chemical packed and shipped?

Tech Serve Solutions expertly packs and ships fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to all relevant transport regulations. Specific packaging details are available upon request.