Nonafluorobutane-1-sulfonic acid
Nonafluorobutane-1-sulfonic acid (CAS: 375-73-5), with the formula CF3(CF2)3SO3H and a molecular weight of 300.10 g/mol, is a potent perfluorinated organic acid. It is characterised by its strong acidic nature and thermal stability, owing to the electron-withdrawing perfluoroalkyl chain. This compound serves as a key building block and reagent in organic synthesis, particularly in the introduction of the nonafluorobutane-1-sulfonyl group into various molecules for materials science and specialty chemical applications.

Fluorinated Surfactant Synthesis
Nonafluorobutane-1-sulfonic acid can be utilised as a precursor in the synthesis of specialty fluorinated surfactants. These surfactants exhibit unique surface tension reduction properties and are valuable in applications requiring high performance under extreme conditions.
Catalyst in Organic Reactions
Due to its strong acidity, this sulfonic acid can function as an effective catalyst in various organic transformations. Its fluorinated nature may offer unique solubility or selectivity profiles compared to conventional acid catalysts.
Precursor for F-Tagged Compounds
As a source of the perfluorobutanesulfonyl moiety, it is employed in creating F-tagged molecules and building blocks. These compounds are of interest in fields such as medicinal chemistry and materials science for modifying properties.
Electrolyte Component Research
Derivatives of nonafluorobutane-1-sulfonic acid are explored for use in electrochemical applications, including advanced battery electrolytes, owing to their chemical and thermal stability.
| Molecular weight | 300.10 |
|---|---|
| Linear formula | CF3(CF2)3SO3H |
| Assay | 97% |
| Boiling point | 112-114 °C/14 mmHg(lit.) |
| Density | 1.811 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.3230(lit.) |
| Storage temperature | 2-8°C |


Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-22-34 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nonafluorobutane-1-sulfonic acid used for?
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Nonafluorobutane-1-sulfonic acid is primarily used as a building block and reagent in organic synthesis, particularly for introducing the nonafluorobutane-1-sulfonyl group. It is also explored in the synthesis of fluorinated surfactants, as a catalyst, and in research for electrolyte components.
What are the CAS number and chemical formula?
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The CAS number is 375-73-5 and the chemical formula is CF3(CF2)3SO3H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nonafluorobutane-1-sulfonic acid with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should Nonafluorobutane-1-sulfonic acid be handled safely?
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Nonafluorobutane-1-sulfonic acid is a Danger hazard, classified as H302 (Harmful if swallowed) and H314 (Causes severe skin burns and eye damage). It reacts violently with water. Handle with extreme caution using appropriate personal protective equipment, including face shields, gloves, and chemical-resistant clothing. Ensure adequate ventilation and avoid contact with water.
How is this chemical packed, shipped, and exported?
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Nonafluorobutane-1-sulfonic acid is packed and shipped according to UN 3265 specifications for corrosive liquids, acidic, organic, n.o.s. (Nonafluorobutane-1-sulfonic acid). As an experienced global supplier, Tech Serve Solutions adheres to all relevant international shipping and export regulations.
How can I request a sample or quote for Nonafluorobutane-1-sulfonic acid?
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To request a sample or a quotation, please contact the Tech Serve Solutions sales team through our website or by phone, providing the product name and CAS number (375-73-5).
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