Nonafluoro-tert-butyl alcohol
Nonafluoro-tert-butyl alcohol (CAS: 2378-02-1), also known as Perfluoro-tert-butyl alcohol, is a fluorinated organic compound with the linear formula (CF3)3COH and a molecular weight of 236.04 g/mol. This highly fluorinated alcohol exhibits unique chemical properties due to the electron-withdrawing nature of the trifluoromethyl groups. It serves as a valuable building block in organic synthesis, particularly for introducing fluorinated moieties into complex molecules for research and development purposes.
- IUPAC
- 1,1,1,3,3,3-Hexafluoro-2-trifluoromethyl-2-propanol,Perfluoro-tert-butyl alcohol
- Synonyms
- 1,1,1,3,3,3-Hexafluoro-2-trifluoromethyl-2-propanolPerfluoro-tert-butyl alcohol

Fluorinated Building Block
Nonafluoro-tert-butyl alcohol is utilised as a key intermediate in the synthesis of advanced fluorinated organic compounds. Its unique structure allows for the introduction of trifluoromethyl groups, which can impart desirable properties such as increased stability and lipophilicity to target molecules.
Specialty Chemical Synthesis
This compound finds application in the development of novel materials and pharmaceuticals where specific fluorinated structural elements are required. Its reactivity and fluorination pattern make it a versatile reagent for complex organic transformations in research settings.
Research and Development
Primarily used in laboratory settings for R&D, Nonafluoro-tert-butyl alcohol enables chemists to explore new synthetic pathways and create novel chemical entities. Its distinct chemical behaviour is of interest in academic and industrial research labs.
| Molecular weight | 236.04 |
|---|---|
| Linear formula | (CF3)3COH |
| Assay | 99% |
| Boiling point | 45 °C(lit.) |
| Density | 1.693 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.3(lit.) |
| Vapour pressure | 5.19 psi (20 °C) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US) |
|---|---|
| Transport (UN / ADR) | UN 2810 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23-36/37/38 |
| Safety statements (S) | 26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nonafluoro-tert-butyl alcohol used for?
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Nonafluoro-tert-butyl alcohol is primarily used as a building block in specialty chemical synthesis and for research and development purposes, enabling the introduction of fluorinated moieties into organic molecules.
What is the CAS number and chemical formula for Nonafluoro-tert-butyl alcohol?
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The CAS number for Nonafluoro-tert-butyl alcohol is 2378-02-1, and its linear formula is (CF3)3COH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nonafluoro-tert-butyl alcohol with an assay of 99%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Nonafluoro-tert-butyl alcohol be handled safely?
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Nonafluoro-tert-butyl alcohol is classified as a Warning substance, with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335), and harmful if inhaled (H332). Appropriate personal protective equipment such as eyeshields, face shields, gloves, and a suitable respirator should be used. Always refer to the Safety Data Sheet (SDS) for comprehensive handling information.
Is Nonafluoro-tert-butyl alcohol a controlled substance?
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The provided data does not indicate that Nonafluoro-tert-butyl alcohol is a controlled substance.
How is Nonafluoro-tert-butyl alcohol packed, shipped, and exported?
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Nonafluoro-tert-butyl alcohol is packed and shipped according to UN 2810, Class 6.1, Packing Group II regulations, reflecting its hazardous nature. As a global supplier, Tech Serve Solutions exports this chemical worldwide.
How can I request a sample or quote for Nonafluoro-tert-butyl alcohol?
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To request a sample or a quotation for Nonafluoro-tert-butyl alcohol, please contact our sales team through the website or by phone, providing your specific requirements and delivery details.
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