Nimustine hydrochloride
Nimustine hydrochloride (CAS 55661-38-6, C9H13ClN6O2) is a research chemical with a molecular weight of 272.69 g/mol. This compound is recognised for its antineoplastic properties, functioning as a DNA intercalator and crosslinker. It is utilized in biochemical research for studies involving apoptosis, cell cycle regulation, and DNA metabolism, contributing to advancements in cell biology and cancer research.
- IUPAC
- N′-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-(2-chloroethyl)-N-nitrosourea hydrochloride
Antineoplastic Research
Nimustine hydrochloride is employed in preclinical research as an antineoplastic agent. Its mechanism of action involves DNA intercalation and crosslinking, which are critical for its cytotoxic effects studied in cancer research.
Apoptosis and Cell Cycle Studies
This compound is a valuable tool for investigating apoptosis and cell cycle regulation. Researchers use it to explore the pathways leading to programmed cell death and to understand disruptions in cell division in various biological contexts.
DNA Metabolism Research
As a DNA intercalator and crosslinker, nimustine hydrochloride is used to study DNA metabolism. It aids in understanding how cells repair DNA damage and maintain genomic integrity.
Cell Biology Investigations
Nimustine hydrochloride serves as a research chemical in cell biology to probe cellular responses to DNA-damaging agents. Its use helps elucidate complex cellular signaling pathways and molecular mechanisms.
| Molecular weight | 272.69 |
|---|---|
| Empirical formula | C9H13ClN6O2 |
| Form | solid |
| Application | Nimustine hydrochloride is an antineoplastic. |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nimustine hydrochloride used for?
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Nimustine hydrochloride is primarily used in research for its antineoplastic properties, aiding studies in apoptosis, cell cycle regulation, DNA metabolism, and cell signaling.
What are the CAS number and formula for Nimustine hydrochloride?
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The CAS number for Nimustine hydrochloride is 55661-38-6, and its empirical formula is C9H13ClN6O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nimustine hydrochloride as a research-grade chemical. We do not represent it as USP, BP, or EP grade. Purity information is available on the product's Certificate of Analysis.
How should Nimustine hydrochloride be handled?
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Nimustine hydrochloride is classified as toxic if swallowed (H301) and requires careful handling. Use appropriate personal protective equipment including eyeshields, face shields, gloves, and P2 respirator cartridges. Follow all safety guidelines as indicated by the Safety Data Sheet (SDS).
How is Nimustine hydrochloride shipped and exported?
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Nimustine hydrochloride is shipped according to international regulations for hazardous materials, including UN 2811 classification. Tech Serve Solutions exports globally, adhering to all necessary compliance requirements.
How can I request a quote or sample?
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To request a quote or a sample of Nimustine hydrochloride, please contact our sales department through the website or by phone, providing your details and desired quantity.
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