Nimodipine

CAS 66085-59-4C21H26N2O7Cell Biology

Nimodipine (CAS 66085-59-4), with the molecular formula C21H26N2O7 and a molecular weight of 418.44 g/mol, is a dihydropyridine derivative primarily utilised as a calcium channel blocker. It is recognised for its vasodilatory properties, particularly in cerebral circulation. Nimodipine is an approved therapeutic agent employed in specific medical contexts to manage neurological conditions related to vascular spasms.

IUPAC: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl 1-methylethyl ester,Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate
Synonyms: Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl 1-methylethyl ester

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Nimodipine (C21H26N2O7) — chemical structure, CAS 66085-59-4; Life Science, fine chemical supplied by Tech Serve Solutions

BayerBioactive Small MoleculesCalcium Channel ModulatorsCell BiologyInhibitors and ActivatorsIon Channels

01 /Applications

Cerebral Vasospasm Management

Nimodipine is prescribed to prevent and treat cerebral vasospasm following subarachnoid haemorrhage. Its selective action on cerebral blood vessels helps to improve blood flow to the brain.

Calcium Channel Modulation

As a calcium channel modulator, Nimodipine affects the influx of calcium ions into vascular smooth muscle cells. This action leads to vasodilation, reducing blood pressure and improving circulation.

Research in Neuroscience

This compound serves as a valuable tool in neuroscience research, aiding investigations into neuronal function, calcium signalling pathways, and neuroprotective mechanisms.

02 /Properties

Molecular weight	418.44
Empirical formula	C21H26N2O7
Form	solid
Colour	white
Solubility	methanol: soluble62.5 mg/mL45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: insolubleH2O: insoluble

03 /Safety & handling

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Warning

Hazard statements

H373May cause damage to organs through prolonged exposure

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	1
Hazard codes (EU)	Xn
Risk statements (R)	48/22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

66085-59-4

MDL number

MFCD00153848

05 /Additional specifications

Gene Information	human ... ADORA3(140), CACNG1(786)rat ... Adora1(29290), Adora2a(25369)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Nimodipine used for?

Nimodipine is used to prevent and treat cerebral vasospasm following subarachnoid haemorrhage. It functions as a calcium channel blocker and is also used in neuroscience research.

What is the CAS number and formula for Nimodipine?

The CAS number for Nimodipine is 66085-59-4, and its molecular formula is C21H26N2O7.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Nimodipine. The specific grade and purity are available upon request. We do not represent this product as USP, BP, or EP grade unless explicitly stated in the product documentation.

What are the safety and handling precautions for Nimodipine?

Nimodipine (CAS 66085-59-4) presents a risk of organ damage through prolonged or repeated exposure (H373). Handling requires a dust mask type N95 (US), eyeshields, and gloves. Users must follow the GHS safety guidelines.