Nabumetone
Nabumetone (CAS: 42924-53-8), a non-steroidal anti-inflammatory drug (NSAID), is a prodrug that is metabolised in the liver to its active form, 6-methoxy-2-naphthylacetic acid. This active metabolite inhibits cyclooxygenase (COX) enzymes, thereby reducing prostaglandin synthesis. Nabumetone is primarily used as an analytical standard for research and quality control purposes within pharmaceutical and biochemical laboratories. Its molecular formula is C15H16O2 with a molecular weight of 228.29 g/mol.
- IUPAC
- 4-(6-Methoxy-2-naphthyl)-2-butanone
Analytical Reference Standard
Used as a certified reference material for the identification and quantification of Nabumetone in pharmaceutical formulations and biological samples. This ensures accuracy in analytical testing and quality control processes.
Pharmacological Research
Serves as a research chemical in studies investigating the mechanisms of action and metabolism of non-steroidal anti-inflammatory drugs (NSAIDs). It aids in understanding drug interactions and efficacy.
Drug Metabolism Studies
Essential for research focused on the metabolic pathways of Nabumetone in biological systems. It is used to identify and quantify metabolites, contributing to pharmacokinetic and pharmacodynamic research.
| Molecular weight | 228.29 |
|---|---|
| Empirical formula | C15H16O2 |
| Grade | analytical standard |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 2 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... PTGS1(5742), PTGS2(5743) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nabumetone used for?
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Nabumetone is used primarily as an analytical reference standard for research and quality control in the pharmaceutical and biochemical industries. It is also used in pharmacological and drug metabolism studies.
What are the CAS number and molecular formula for Nabumetone?
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The CAS number for Nabumetone is 42924-53-8, and its molecular formula is C15H16O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nabumetone as an analytical standard. The specific purity and assay are detailed in the product's specification sheet. We do not represent this product as USP, BP, or EP grade unless explicitly stated in the specifications.
How should Nabumetone be handled and stored?
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Handle Nabumetone with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store in a cool, dry place away from incompatible materials. Consult the Safety Data Sheet for detailed handling and storage instructions.
Is Nabumetone a controlled substance?
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Based on the provided data, Nabumetone is not indicated as a controlled substance. For definitive information, please consult relevant national and international regulations.
How can I get a quote or request a sample of Nabumetone?
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To request a quote or a sample of Nabumetone, please contact the Tech Serve Solutions sales department via our website or by phone, providing your details and the product's CAS number (42924-53-8).
How is Nabumetone packed and shipped?
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Nabumetone is carefully packed according to industry best practices to ensure stability during transit. As a global supplier, Tech Serve Solutions has extensive experience in exporting chemicals worldwide, adhering to all necessary shipping regulations.
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