5-Bromo-2,3-difluorophenol
5-Bromo-2,3-difluorophenol (CAS: 186590-26-1) is a specialised organic building block with the molecular formula C6H3BrF2O. This halogenated phenol derivative is characterised by its unique substitution pattern, making it a valuable intermediate in complex organic synthesis. Its primary applications lie in the research and development of novel chemical entities, particularly within the pharmaceutical and agrochemical sectors, where precise molecular architecture is crucial for biological activity.
- Synonyms
- C6H3BrF2O

Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. The bromine and fluorine substituents offer versatile handles for further chemical modification in drug discovery programmes.
Agrochemical Synthesis
Serves as a key building block for developing new pesticides, herbicides, and fungicides. Its structure can be incorporated into molecules designed for specific biological targets in crop protection.
Materials Science Research
Applicable in the creation of novel materials and functional polymers. The presence of halogens can influence properties such as flame retardancy or electronic characteristics.
Organic Synthesis Reagent
A useful reagent for introducing the 2,3-difluorophenoxy moiety into organic molecules. It facilitates the construction of complex aromatic systems in academic and industrial research laboratories.
| Molecular weight | 208.99 |
|---|---|
| Empirical formula | C6H3BrF2O |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Bromo-2,3-difluorophenol used for?
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5-Bromo-2,3-difluorophenol is primarily used as an intermediate in organic synthesis, particularly in the research and development of pharmaceuticals, agrochemicals, and novel materials. It functions as a versatile building block for introducing specific fluorinated and brominated aromatic structures into target molecules.
What are the CAS number and formula for 5-Bromo-2,3-difluorophenol?
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The CAS number for 5-Bromo-2,3-difluorophenol is 186590-26-1, and its empirical formula (Hill notation) is C6H3BrF2O.
What grade and purity does Tech Serve Solutions supply for 5-Bromo-2,3-difluorophenol?
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Tech Serve Solutions supplies 5-Bromo-2,3-difluorophenol as a research or technical grade chemical. The precise assay and purity are detailed in the product's specification sheet. TSS does not represent this product as USP, BP, EP, or suitable for pharmaceutical, food, or cosmetic applications.
How should 5-Bromo-2,3-difluorophenol be handled safely?
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5-Bromo-2,3-difluorophenol is classified as a Warning substance. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including gloves, eye protection, and in a well-ventilated area or fume hood. Avoid breathing dust/fume/gas/mist/vapours/spray.
Is 5-Bromo-2,3-difluorophenol a controlled substance?
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The provided data does not indicate that 5-Bromo-2,3-difluorophenol is a controlled substance under standard chemical regulations. However, customers should verify local regulations regarding its use and handling.
How is 5-Bromo-2,3-difluorophenol packed and shipped?
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5-Bromo-2,3-difluorophenol is carefully packed according to industry best practices to ensure safe transit. TSS exports chemicals globally, adhering to all relevant shipping and customs regulations.
How can I request a quote or sample for 5-Bromo-2,3-difluorophenol?
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To request a quote or a sample of 5-Bromo-2,3-difluorophenol, please use the 'Request a Quote' or 'Sample Request' forms available on our website, or contact our sales team directly via email or phone.
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