4-Bromophenylhydrazine hydrochloride
4-Bromophenylhydrazine hydrochloride (CAS 622-88-8) is an organic compound with the linear formula BrC<sub>6</sub>H<sub>4</sub>NHNH<sub>2</sub>·HCl and a molecular weight of 223.50 g/mol. This hydrazine derivative serves as a valuable reagent in organic synthesis. It is primarily utilised as a building block for the creation of more complex molecules, including acylsulfonamides, acylsulfamides, and specific indolo[3,2-d][1]benzazepinone structures, finding applications in chemical research and development.

Synthesis of Acylsulfonamides and Acylsulfamides
4-Bromophenylhydrazine hydrochloride is employed as a key reagent in the laboratory synthesis of acylsulfonamides and acylsulfamides. These compounds are of interest in medicinal chemistry and materials science.
Precursor for Indolo[3,2-d][1]benzazepin-6(5H)-one Derivatives
This hydrazine is a documented precursor in the synthesis of complex polycyclic compounds such as 9-bromo-2-ethenyl-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one. Such structures are investigated for their potential biological activities.
Organic Synthesis Building Block
As a functionalised hydrazine, 4-Bromophenylhydrazine hydrochloride acts as a versatile building block in diverse organic synthesis pathways. It enables the introduction of the 4-bromophenylhydrazine moiety into target molecules.
| Molecular weight | 223.50 |
|---|---|
| Linear formula | BrC6H4NHNH2·HCl |
| Assay | 99% |
| Application | 4-Bromophenylhydrazine hydrochloride was used as reagent in the synthesis of:• acylsulfonamides and acylsulfamides1• 9-bromo-2-ethenyl-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one2 |
| Melting point | 220-230 °C (dec.)(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromophenylhydrazine hydrochloride used for?
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4-Bromophenylhydrazine hydrochloride is used as a reagent and building block in organic synthesis, notably for preparing acylsulfonamides, acylsulfamides, and complex heterocyclic structures like indolo[3,2-d][1]benzazepinones.
What are the CAS number and chemical formula for 4-Bromophenylhydrazine hydrochloride?
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The CAS number is 622-88-8, and the linear formula is BrC<sub>6</sub>H<sub>4</sub>NHNH<sub>2</sub>·HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromophenylhydrazine hydrochloride with an assay of 99%. This is a technical/research grade product, and we do not represent it as USP, BP, or EP.
What are the main hazards associated with 4-Bromophenylhydrazine hydrochloride?
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This compound is classified under GHS05 with the signal word 'Danger' and carries the hazard statement H314, indicating it causes severe skin burns and eye damage. Appropriate personal protective equipment, including eyeshields, face shields, and chemical-resistant gloves, is essential during handling. Respiratory protection may also be required.
Is 4-Bromophenylhydrazine hydrochloride suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Bromophenylhydrazine hydrochloride, adhering to all necessary international shipping regulations. For specific destination requirements, please contact our export department.
How can I request a sample or quote for 4-Bromophenylhydrazine hydrochloride?
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To request a sample or obtain a quotation for 4-Bromophenylhydrazine hydrochloride, please use the 'Request a Quote' or 'Sample Request' form on our website, or contact our sales team directly via email or phone.
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