(−)-N6-(2-Phenylisopropyl)adenosine

CAS 38594-96-6C19H23N5O4Biochemicals & Reagents

(−)-N6-(2-Phenylisopropyl)adenosine (CAS 38594-96-6) is a synthetic adenosine derivative with the molecular formula C19H23N5O4 and a molecular weight of 385.42 g/mol. This compound acts as a potent agonist for A1 adenosine receptors, making it a valuable tool in biochemical and pharmacological research. It is primarily utilised in studies investigating cell signalling pathways, neuroscience, and the function of purinergic receptors. Supplied as a white solid, it is available for research and development purposes.

IUPAC: (R)-N6-(1-Methyl-2-phenylethyl)adenosine,N6-(L-2-Phenylisopropyl)adenosine,R-(−)-PIA
Synonyms: N6-(L-2-Phenylisopropyl)adenosineR-(−)-PIA(R)-N6-(1-Methyl-2-phenylethyl)adenosine

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(−)-N6-(2-Phenylisopropyl)adenosine (C19H23N5O4) — chemical structure, CAS 38594-96-6; Life Science, fine chemical supplied by Tech Serve Solutions

AgonistsBioactive Small MoleculesBiochemicals and ReagentsCell BiologyGPCR ModulatorsGPCR ProteinsModulators and AntibodiesNeuroscienceNeurotransmissionNeurotransmitters

01 /Applications

Pharmacological Research

Serves as a selective A1 adenosine receptor agonist, enabling detailed investigation into receptor function and downstream signalling cascades in various biological systems.

Neuroscience Studies

Utilised in neuroscience research to probe the role of adenosine in neurotransmission and neuromodulation, contributing to the understanding of neurological processes.

Biochemical Assays

Employed as a standard or tool compound in biochemical assays designed to identify and characterise molecules interacting with adenosine receptors.

Cell Signalling Investigations

Facilitates research into cellular responses mediated by adenosine signalling, particularly within the central nervous system and cardiovascular system.

02 /Properties

Molecular weight	385.42
Empirical formula	C19H23N5O4
Form	solid
Colour	white
Solubility	H2O: slightly soluble0.3 mg/mL (Solutions may be stored for several days at 4°C.)45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble1.6 mg/mL (Solutions may be stored for several days at 4°C.)
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

38594-96-6

MDL number

MFCD00069194

PubChem substance

24277681

05 /Additional specifications

Gene Information	human ... ADORA1(134)
Potency	1.17 nM Ki for A1 receptors (using [3H]CHA in rat forebrain preparations)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is (–)-N6-(2-Phenylisopropyl)adenosine used for?

(–)-N6-(2-Phenylisopropyl)adenosine is used as a selective A1 adenosine receptor agonist in pharmacological and neuroscience research, particularly for studying cell signalling pathways and neurotransmission.

What is the CAS number and chemical formula?

The CAS number is 38594-96-6 and the chemical formula is C19H23N5O4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this compound as a research-grade chemical. The specific purity is not detailed in the provided data; therefore, TSS does not represent it as USP, BP, or EP grade.

What are the safety and handling recommendations?

Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter is recommended. Dispose of in accordance with environmental regulations, as indicated by WGK Germany 3.

How is this chemical shipped or exported?

This chemical is typically stored at 2-8°C. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, handling all necessary export documentation.