N,N-Diethylnicotinamide
N,N-Diethylnicotinamide (CAS 59-26-7), also known as nikethamide, is the diethylamide of nicotinic acid, with the molecular formula C10H14N2O and a molar mass of 178.23 g/mol. It is a pyridine-based heterocyclic compound supplied as a colourless to pale liquid at room temperature. Tech Serve Solutions offers it at 99% assay as a research and synthesis reagent and as a pharmaceutical reference substance, serving buyers searching for a reliable N,N-Diethylnicotinamide supplier, manufacturer and exporter.
- IUPAC
- ‘Nikethamide’,Nicotinic acid diethylamide
- Synonyms
- NikethamideNicotinic acid diethylamideN,N-DiethylnicotinamideN,N-Diethylpyridine-3-carboxamide3-Pyridinecarboxylic acid diethylamideCoramineCAS 59-26-7
Pyridine building block for organic synthesis
Serves as a heterocyclic intermediate and C10 building block in the preparation of substituted pyridines and nicotinic acid derivatives. The diethylamide group offers a defined handle for further functionalisation in multi-step routes.
Pharmaceutical reference and intermediate
N,N-Diethylnicotinamide is the active substance nikethamide, historically used as an analeptic. It is used as a reference substance and intermediate in pharmaceutical research and quality-control work.
Laboratory reagent and reference standard
The 99% assay grade suits use as a laboratory reagent and characterised reference material for analytical method development, identification and comparison studies.
Research and method development
Used in academic and industrial laboratories for reaction screening, derivatisation studies and the investigation of nicotinamide chemistry where a well-defined liquid amide is required.
| Molecular weight | 178.23 |
|---|---|
| Empirical formula | C10H14N2O |
| Assay | 99% |
| Boiling point | 296-300 °C(lit.) |
| Density | 1.06 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.524(lit.) |
| Melting point | 23 °C(lit.) |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N,N-Diethylnicotinamide used for?
+
It is used mainly as a pyridine-based building block and intermediate in organic and pharmaceutical synthesis, and as a laboratory reagent and reference substance. N,N-Diethylnicotinamide is also known as nikethamide, the diethylamide of nicotinic acid. We supply it for research, synthesis and quality-control applications and do not provide medical or dosing advice.
What is the CAS number and molecular formula of N,N-Diethylnicotinamide?
+
The CAS number is 59-26-7 and the EC number is 200-418-5. The molecular formula is C10H14N2O, with a molecular weight of 178.23 g/mol. The MDL number is MFCD00006386 and the Beilstein registry number is 5743.
What grade and purity does Tech Serve Solutions supply?
+
We supply N,N-Diethylnicotinamide at a typical assay of 99% as a research and synthesis-grade reagent. Unless a specific specification is agreed in writing, we do not represent it as USP, BP or EP pharmacopoeia grade. A certificate of analysis is provided with each batch, and documentation can be reviewed against your requirements before despatch.
What are the safety and handling requirements for N,N-Diethylnicotinamide?
+
This product is hazardous. It carries GHS pictogram GHS06 with the signal word Danger and the hazard statements H301 (toxic if swallowed), H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Handle with gloves, eye and face protection and suitable respiratory protection in a well-ventilated area, and avoid ingestion, skin and eye contact. Consult the Safety Data Sheet before use.
How is N,N-Diethylnicotinamide packed, shipped and exported?
+
It is packed in appropriate sealed containers for liquids and labelled to GHS standards. For transport it is classified as UN 2811, Class 6.1, Packing Group III, and is shipped in line with applicable dangerous-goods regulations. We export worldwide with full documentation, including the certificate of analysis and Safety Data Sheet; pack sizes can be matched to laboratory or bulk requirements.
Is N,N-Diethylnicotinamide a controlled substance?
+
N,N-Diethylnicotinamide (nikethamide) is not scheduled under the international drug-control conventions. However, national and sporting regulations may apply in some jurisdictions, so buyers are responsible for confirming and complying with the rules that govern import and use in their own country.
How do I request a sample or quote?
+
Contact Tech Serve Solutions with the quantity, required pack size and destination, and our team will respond with availability, lead time and export documentation. Samples can be arranged subject to regulatory and transport requirements for this compound.
▶ Related products
4-Amino-2-chloropyridine
C5H5ClN2
Heterocyclic Building Blocks
4-Ethynyl-1-methyl-1H-pyrazole
C6H6N2
Heterocyclic Building Blocks
4-Hydroxyquinoline-3-carboxylic acid ethyl ester
C12H11NO3
Heterocyclic Building Blocks
4-isocyanatopyridine
C6H4N2O
Heterocyclic Building Blocks
5-Chloro-2,8-dimethylquinoline
Heterocyclic Building Blocks
5-Chloro-2-methylene-1,3,3-trimethylindoline
Heterocyclic Building Blocks
5-Chloro-2-thiophenecarbonitrile
Heterocyclic Building Blocks
5-ethynyl-1H-pyrazole
C5H4N2
Heterocyclic Building Blocks▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis