N-(Chloromethyl)phthalimide
N-(Chloromethyl)phthalimide (CAS: 17564-64-6) is an organic compound with the empirical formula C9H6ClNO2 and a molecular weight of 195.60 g/mol. It is a valuable building block in organic synthesis, particularly for introducing the phthalimidomethyl group. This compound is commonly employed in the preparation of various organic intermediates and fine chemicals, serving as a key reagent in multi-step synthetic pathways. Its utility is recognised in academic research and industrial chemical manufacturing.
Organic Synthesis Reagent
N-(Chloromethyl)phthalimide acts as a versatile electrophilic reagent for alkylation reactions. It is used to introduce the phthalimidomethyl moiety onto nucleophiles such as amines, thiols, and alcohols.
Pharmaceutical Intermediate Synthesis
This compound serves as a critical building block in the synthesis of complex organic molecules, including potential pharmaceutical intermediates. Its structure allows for controlled functionalisation in drug discovery research.
Fine Chemical Manufacturing
N-(Chloromethyl)phthalimide is utilised in the broader fine chemical industry for the production of specialised organic compounds. Its reactivity profile makes it suitable for various bespoke chemical syntheses.
| Molecular weight | 195.60 |
|---|---|
| Empirical formula | C9H6ClNO2 |
| Assay | 97% |
| Solubility | chloroform: soluble50 mg/mL |
| Melting point | 131-135 °C(lit.) |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38-43-52/53 |
| Safety statements (S) | 26-36-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(Chloromethyl)phthalimide used for?
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N-(Chloromethyl)phthalimide is primarily used as a reagent in organic synthesis to introduce the phthalimidomethyl group and as a building block for pharmaceutical intermediates and fine chemicals.
What are the CAS number and formula for N-(Chloromethyl)phthalimide?
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The CAS number for N-(Chloromethyl)phthalimide is 17564-64-6, and its empirical formula is C9H6ClNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-(Chloromethyl)phthalimide with a minimum purity of 97%. We do not represent this product as meeting any pharmacopoeia standards (e.g., USP, BP, EP).
How should N-(Chloromethyl)phthalimide be handled safely?
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Handle N-(Chloromethyl)phthalimide with appropriate personal protective equipment, including a dust mask (N95 US), eyeshields, faceshields, and gloves. Ensure good ventilation. Refer to the Safety Data Sheet for full handling and hazard information. It is classified as GHS06 with a Danger signal word, indicating significant acute toxicity and irritant properties.
How is N-(Chloromethyl)phthalimide shipped and exported?
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N-(Chloromethyl)phthalimide is classified under UN 2811, 6.1 / PGIII for transport. Tech Serve Solutions is experienced in exporting chemicals globally, adhering to all relevant shipping regulations.
How can I request a sample or quote for N-(Chloromethyl)phthalimide?
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To request a sample or a quotation for N-(Chloromethyl)phthalimide, please use the contact form on our website or contact our sales department directly.
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