N-(Diphenylmethylene)aminoacetonitrile
N-(Diphenylmethylene)aminoacetonitrile (CAS 70591-20-7) is an organic compound with the linear formula (C6H5)2C=NCH2CN and a molecular weight of 220.27. This chemical serves as a valuable building block in organic synthesis. Its applications include the preparation of various substituted phenylalanine amides and amino acid esters, demonstrating its utility in complex molecule construction and medicinal chemistry research.
Synthesis of Phenylalanine Derivatives
N-(Diphenylmethylene)aminoacetonitrile has been employed in the synthesis of ring-substituted phenylalanine amides and analogs like o-carboranylalanine, contributing to the development of novel amino acid derivatives.
Enantioselective Synthesis
This compound plays a role as a key intermediate in the concise, enantioselective synthesis of molecules such as dehydrocoronamic acid ethyl ester.
Preparation of Gamma-Amino Acid Esters
It is utilized in synthetic routes for producing gamma-amino acid esters, highlighting its versatility in constructing diverse organic frameworks.
| Molecular weight | 220.27 |
|---|---|
| Linear formula | (C6H5)2C=NCH2CN |
| Assay | 98% |
| Solubility | 95% ethanol: soluble50 mg/mL, clear, colorless to faintly yellow |
| Storage temperature | 2-8°C |
| Application | N-(Diphenylmethylene)aminoacetonitrile has been used in:• synthesis of ring-substituted phenylalanine amides1 and o-carboranylalanine, a potential analog of phenylalanine2• a key enantiodifferentiating step in concise synthesis of dehydrocoronamic acid ethyl ester3• synthesis of γ-amino acid esters4 |
| Melting point | 84-85 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(Diphenylmethylene)aminoacetonitrile used for?
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N-(Diphenylmethylene)aminoacetonitrile is used as a building block in chemical synthesis, particularly for preparing phenylalanine derivatives, dehydrocoronamic acid ethyl ester, and gamma-amino acid esters.
What is the CAS number and formula for N-(Diphenylmethylene)aminoacetonitrile?
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The CAS number is 70591-20-7, and the linear formula is (C6H5)2C=NCH2CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-(Diphenylmethylene)aminoacetonitrile with an assay of 98%. This is a research-grade chemical and is not represented as USP, BP, EP, or any other pharmacopoeia standard.
How should N-(Diphenylmethylene)aminoacetonitrile be handled?
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Handling requires appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. It is classified with GHS07, a warning signal word, and carries hazard statements including H302, H312, H315, H319, H332, and H335, indicating it is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and eye irritation, and may cause respiratory irritation.
How is N-(Diphenylmethylene)aminoacetonitrile packed and shipped?
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N-(Diphenylmethylene)aminoacetonitrile is typically stored at 2-8°C. It is packed according to industry standards for safe transport and is available for global export by Tech Serve Solutions.
How can I request a quote or sample?
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To request a quote or a sample of N-(Diphenylmethylene)aminoacetonitrile, please contact the Tech Serve Solutions sales department via our website or listed contact details.
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