N-(Hydroxymethyl)phthalimide
N-(Hydroxymethyl)phthalimide (CAS: 118-29-6), a white to off-white crystalline solid with the molecular formula C9H7NO3 and a molecular weight of 177.16 g/mol, serves as a valuable organic building block. Its primary application lies in the amidomethylation of aromatic compounds, particularly within triflic acid reaction systems. Supplied by Tech Serve Solutions, this compound is essential for various chemical synthesis pathways, offering a reliable intermediate for further molecular elaboration in research and development settings.
- IUPAC
- Phthalimidomethanol
Amidomethylation Reagent
N-(Hydroxymethyl)phthalimide is employed for the amidomethylation of aromatic substrates. This reaction is typically conducted in the presence of strong acids, such as triflic acid, to facilitate the introduction of a phthalimidomethyl group onto the aromatic ring.
Organic Synthesis Intermediate
As a functionalized cyclic imide, it acts as a versatile intermediate in organic synthesis. The phthalimide moiety can be readily cleaved, allowing for the controlled release of a primary amine after the amidomethylation step, making it useful for constructing more complex molecules.
Research and Development
This compound is utilised in laboratory settings for exploring novel synthetic routes and developing new chemical entities. Its well-defined reactivity makes it a predictable component in multi-step syntheses within academic and industrial research.
| Molecular weight | 177.16 |
|---|---|
| Empirical formula | C9H7NO3 |
| Assay | ≥98.0% (HPLC) |
| Application | For amidomethylation of aromatics in triflic acid.1 |
| Melting point | 140-145 °C147-149 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(Hydroxymethyl)phthalimide used for?
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N-(Hydroxymethyl)phthalimide is primarily used for the amidomethylation of aromatic compounds, often in the presence of triflic acid, and as a general intermediate in organic synthesis.
What is the CAS number and chemical formula for N-(Hydroxymethyl)phthalimide?
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The CAS number is 118-29-6 and the chemical formula is C9H7NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-(Hydroxymethyl)phthalimide with a purity of ≥98.0% (HPLC). TSS does not represent this product as USP, BP, or EP grade unless explicitly stated in the product specifications.
What are the key safety considerations when handling N-(Hydroxymethyl)phthalimide?
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Handling N-(Hydroxymethyl)phthalimide requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Consult the Safety Data Sheet for full hazard information and handling procedures.
Is N-(Hydroxymethyl)phthalimide a controlled substance?
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The provided data does not indicate that N-(Hydroxymethyl)phthalimide is a controlled substance.
How can I request a quote or sample of N-(Hydroxymethyl)phthalimide?
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To request a quote or sample, please contact our sales team through the Tech Serve Solutions website or by phone, referencing the product name and CAS number (118-29-6).
How is N-(Hydroxymethyl)phthalimide packaged, shipped, and exported?
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N-(Hydroxymethyl)phthalimide is carefully packaged to ensure product integrity during transit. We are experienced in exporting fine chemicals globally, adhering to all relevant international shipping regulations.
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