N-Acetyl-Arg-Gly-Lys(acetyl)-7-amido-4-methylcoumarin trifluoroacetate salt
N-Acetyl-Arg-Gly-Lys(acetyl)-7-amido-4-methylcoumarin trifluoroacetate salt (CAS 660846-97-9) is a fluorogenic substrate with the empirical formula C28H40N8O7 · xC2HF3O2. This compound is specifically designed as a novel fluorogenic assay for the activity of histone deacetylases. Supplied by Tech Serve Solutions, it serves as a valuable reagent in biochemical research and enzymatic studies, offering precise detection capabilities.
- IUPAC
- N2-Acetyl-L-arginylglycyl-N3-acetyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-lysinamide trifluoroacetate salt,Ac-Arg-Gly-Lys(Ac)-AMC
- Synonyms
- Ac-Arg-Gly-Lys(Ac)-AMCN2-Acetyl-L-arginylglycyl-N3-acetyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-lysinamide trifluoroacetate salt
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Histone Deacetylase (HDAC) Activity Assays
Utilised as a fluorogenic substrate for the quantitative measurement of histone deacetylase (HDAC) activity. Upon cleavage by HDACs, it releases a fluorescent moiety (7-amino-4-methylcoumarin), enabling sensitive detection and quantification of enzyme activity in various biological contexts.
Enzymatic Research Reagent
A key reagent for researchers investigating enzyme kinetics and mechanisms, particularly those involving proteases or enzymes that recognise and process specific peptide sequences. Its defined structure allows for controlled studies of enzyme-substrate interactions.
Biochemical Studies
Employed in biochemical assays to probe cellular processes influenced by HDACs. This includes studies on gene expression, chromatin remodelling, and other epigenetic regulatory mechanisms where HDAC activity plays a significant role.
| Empirical formula | C28H40N8O7 · xC2HF3O2 |
|---|---|
| Assay | ≥98% (HPLC) |
| Storage temperature | −20°C |
| Application | Novel fluorogenic assay for histone deacetylase activity1. |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Acetyl-Arg-Gly-Lys(acetyl)-7-amido-4-methylcoumarin trifluoroacetate salt used for?
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This compound is a fluorogenic substrate primarily used for the assay of histone deacetylase (HDAC) activity, enabling sensitive detection and quantification of enzyme function in biochemical research.
What are the CAS number and formula for this product?
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The CAS number for the free base is 660846-97-9. The empirical formula is C28H40N8O7 · xC2HF3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥98% purity determined by HPLC. This product is supplied for research purposes and is not intended for pharmaceutical, medical, or other end-use applications, nor is it represented as USP, BP, EP, or pharmacopoeia grade.
How should N-Acetyl-Arg-Gly-Lys(acetyl)-7-amido-4-methylcoumarin trifluoroacetate salt be handled and stored?
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Handle with appropriate laboratory precautions. The safety data indicates a Wassergefährdungsklasse (WGK) of 3 in Germany. For optimal stability, store at −20°C.
Is this chemical controlled or scheduled?
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The provided data does not indicate that this chemical is controlled or scheduled under any regulations relevant to its supply for research and laboratory use.
How can I get a quote or request a sample?
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To request a quote or a sample, please contact our sales team directly through the Tech Serve Solutions website or by calling our customer service line. Please reference the product name and CAS number.
How is this product packed, shipped, or exported?
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Products are carefully packed according to international shipping regulations for fine chemicals. Tech Serve Solutions is an experienced global exporter and can provide necessary documentation for international orders.
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