N-(7-Dimethylamino-4-methyl-3-coumarinyl)maleimide
N-(7-Dimethylamino-4-methyl-3-coumarinyl)maleimide (CAS: 55145-14-7), with the molecular formula C16H14N2O4 and a molecular weight of 298.29 g/mol, is a fluorescent reagent. It is primarily utilised for its sensitive detection capabilities, particularly in biochemical applications and as a carbohydrate label. Its fluorescent properties, with excitation at 398 nm and emission at 482 nm after derivatisation, make it valuable for various analytical techniques.
- IUPAC
- DACM-3
Fluorescent Labeling Reagent
This compound serves as a fluorescent label, enabling the sensitive detection and quantification of target molecules in various biological and chemical assays. Its specific fluorescence characteristics are useful in analytical procedures.
Biochemical Detection
N-(7-Dimethylamino-4-methyl-3-coumarinyl)maleimide is employed in biochemical research for the detection of specific functional groups. Its ability to form fluorescent adducts aids in identifying and studying biomolecules.
Chromatography Applications
As a carbohydrate label for chromatography, this reagent can be used to derivatize analytes, enhancing their detectability via fluorescence detection in chromatographic separations.
Fluorescent Probes
The compound functions as a fluorescent probe, aiding in the visualisation and study of cellular processes or molecular interactions where fluorescence microscopy is applied.
| Molecular weight | 298.29 |
|---|---|
| Empirical formula | C16H14N2O4 |
| Assay | ≥99.0% (HPLC) |
| Grade | for fluorescence |
| Melting point | 218-220 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37/38 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 398 nm; λem 482 nm in 0.1 M phosphate pH 7.0 (after derivatization with 2-mercaptoethanol) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(7-Dimethylamino-4-methyl-3-coumarinyl)maleimide used for?
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N-(7-Dimethylamino-4-methyl-3-coumarinyl)maleimide is primarily used as a fluorescent labeling reagent for biochemical detection and as a carbohydrate label for chromatography and other analytical techniques requiring fluorescence detection.
What is the CAS number and molecular formula?
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The CAS number is 55145-14-7 and the molecular formula is C16H14N2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product for fluorescence applications with an assay of ≥99.0% (HPLC). We do not represent this product as USP, EP, BP, or any other pharmacopoeia grade.
What are the safety considerations for handling this chemical?
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This compound is classified as a Warning, with hazard statements H315 (Causes skin irritation) and H335 (May cause respiratory irritation). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle with adequate ventilation and avoid dust formation.
Is this product available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and this product can be packed and shipped internationally.
How can I request a sample or quote?
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To request a sample or a quotation, please contact our sales department via the details provided on our website.
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