N-(5-Hydroxypentyl)trifluoroacetamide
N-(5-Hydroxypentyl)trifluoroacetamide (CAS: 128238-44-8) is a trifluoroacetylated amino alcohol with the molecular formula C7H12F3NO2 and a molecular weight of 199.17 g/mol. This compound serves as a versatile building block in organic synthesis, particularly valuable for its bifunctional nature. It is utilised in chemical research, synthesis, and the development of chemical biology tools, acting as a linker in various molecular architectures.
- IUPAC
- 5-(Trifluoroacetamido)-1-pentanol

Organic Synthesis Intermediate
N-(5-Hydroxypentyl)trifluoroacetamide is employed as a key intermediate in the synthesis of complex organic molecules. Its trifluoroacetamide group offers a stable, yet cleavable, amine protection, while the hydroxyl group allows for further functionalization.
Bifunctional Linker Development
The distinct reactive sites (protected amine and primary alcohol) make this compound an ideal candidate for constructing bifunctional linkers. These linkers are crucial in bioconjugation chemistry and the development of modified biomolecules.
Chemical Biology Research
Researchers in chemical biology can utilise this compound to introduce specific structural elements into probes or molecular systems. Its properties lend themselves to applications requiring precise molecular modification and functionalization.
Building Block for Specialty Chemicals
As an organic building block, N-(5-Hydroxypentyl)trifluoroacetamide is used in the creation of specialty chemicals, offering a pathway to novel compounds with tailored properties for diverse research and industrial applications.
| Molecular weight | 199.17 |
|---|---|
| Empirical formula | C7H12F3NO2 |
| Assay | ≥98.0% (GC) |
| Density | 1.248 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.420 |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 109 °C / 228.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(5-Hydroxypentyl)trifluoroacetamide used for?
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N-(5-Hydroxypentyl)trifluoroacetamide is primarily used as a versatile building block in organic synthesis, for constructing bifunctional linkers, in chemical biology research, and for creating specialty chemicals.
What are the CAS number and formula for N-(5-Hydroxypentyl)trifluoroacetamide?
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The CAS number is 128238-44-8 and the empirical formula is C7H12F3NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-(5-Hydroxypentyl)trifluoroacetamide with a purity of ≥98.0% (GC). This is typically considered a research or technical grade, and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the main hazards associated with N-(5-Hydroxypentyl)trifluoroacetamide?
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N-(5-Hydroxypentyl)trifluoroacetamide is classified with GHS07 symbol and a Warning signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields and gloves, should be used during handling.
How is N-(5-Hydroxypentyl)trifluoroacetamide packed, shipped, and exported?
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N-(5-Hydroxypentyl)trifluoroacetamide is available from Tech Serve Solutions and is prepared for safe and compliant packing, shipping, and international export, adhering to all relevant regulations.
How can I request a sample or quote for N-(5-Hydroxypentyl)trifluoroacetamide?
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To request a sample or a quote for N-(5-Hydroxypentyl)trifluoroacetamide, please contact our sales department through the website or by phone.
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