N-(6-Hydroxyhexyl)trifluoroacetamide
N-(6-Hydroxyhexyl)trifluoroacetamide (CAS: 40248-34-8; Formula: C8H14F3NO2; MW: 213.20) is a valuable organic compound featuring both a hydroxyl group and a trifluoroacetamide moiety. This bifunctional nature makes it a versatile building block in chemical synthesis. It is primarily employed as an intermediate in the development of complex molecules, particularly within pharmaceutical research and chemical biology applications, where precise molecular modifications are required.
- IUPAC
- 6-(Trifluoroacetamido)-1-hexanol
Organic Synthesis Intermediate
Serves as a key building block in multi-step organic syntheses. Its terminal hydroxyl group allows for esterification, etherification, or oxidation, while the trifluoroacetamide group can be involved in various coupling reactions or deprotection strategies.
Pharmaceutical Research
Utilised in the synthesis of potential drug candidates and biologically active molecules. The trifluoroacetyl group can influence lipophilicity and metabolic stability, properties often explored in medicinal chemistry.
Chemical Biology Tools
Incorporated into probes or modified biomolecules for studying biological processes. The distinct chemical handles allow for selective conjugation or functionalisation in complex biological systems.
Linker and Crosslinker Design
The bifunctional nature lends itself to the design of linkers for conjugating different molecular entities. The hexyl chain provides a flexible spacer of defined length.
| Molecular weight | 213.20 |
|---|---|
| Empirical formula | C8H14F3NO2 |
| Assay | ≥98.0% (GC) |
| Melting point | 46-49 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(6-Hydroxyhexyl)trifluoroacetamide used for?
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N-(6-Hydroxyhexyl)trifluoroacetamide is primarily used as a versatile building block and intermediate in organic synthesis, particularly for pharmaceutical research and chemical biology applications.
What are the CAS number and chemical formula for N-(6-Hydroxyhexyl)trifluoroacetamide?
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The CAS number is 40248-34-8, and the empirical formula is C8H14F3NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-(6-Hydroxyhexyl)trifluoroacetamide with an assay of ≥98.0% (GC). This product is supplied for research and development purposes. Tech Serve Solutions does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should N-(6-Hydroxyhexyl)trifluoroacetamide be handled safely?
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This compound is classified as a Warning, with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, in a well-ventilated area. Refer to the Safety Data Sheet for full handling instructions.
Is N-(6-Hydroxyhexyl)trifluoroacetamide a controlled substance?
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The provided data does not indicate that N-(6-Hydroxyhexyl)trifluoroacetamide is a controlled substance.
How is N-(6-Hydroxyhexyl)trifluoroacetamide packed and shipped?
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N-(6-Hydroxyhexyl)trifluoroacetamide is carefully packed to ensure safe transit and is exported globally by Tech Serve Solutions.
How can I request a quote or sample?
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To request a quote or sample of N-(6-Hydroxyhexyl)trifluoroacetamide, please contact our sales team through the website or by phone, providing your specific requirements.
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