N-(3-tert-Butylsulfanyl-pyridin-4-yl)-2,2-dimethyl-propionamide
N-(3-tert-Butylsulfanyl-pyridin-4-yl)-2,2-dimethyl-propionamide (CAS 766557-59-9) is a heterocyclic building block with the molecular formula C14H22N2OS and a molar mass of 266.40 g/mol. The molecule combines a 4-aminopyridine core protected as a pivalamide with a tert-butylsulfanyl (tert-butylthio) substituent at the 3-position. It is supplied as a research-grade fine chemical, used principally as a synthetic intermediate in pharmaceutical and medicinal-chemistry research. Tech Serve Solutions supplies it to laboratories worldwide.
- Synonyms
- N-(3-tert-Butylsulfanyl-pyridin-4-yl)-2,2-dimethyl-propionamideN-(3-(tert-Butylthio)pyridin-4-yl)pivalamideN-[3-(tert-butylsulfanyl)pyridin-4-yl]-2,2-dimethylpropanamideN-[3-(tert-butylthio)pyridin-4-yl]-2,2-dimethylpropanamide2,2-dimethyl-N-[3-(tert-butylsulfanyl)pyridin-4-yl]propanamideCAS 766557-59-9
Heterocyclic building block
Serves as a functionalised pyridine scaffold for multi-step organic synthesis. The 4-position carries a pivalamide (2,2-dimethylpropionamide) group while the 3-position bears a tert-butylthio substituent, giving chemists two distinct handles for further elaboration.
Pharmaceutical and medicinal-chemistry research
Used as an intermediate in the preparation of pyridine-based candidate molecules and analogue libraries. Its protected amino-pyridine motif is a common feature in discovery-stage synthetic routes.
Directed metalation and functionalisation
The pivalamide acts as a directing and protecting group on the aminopyridine, which can support regioselective metalation and downstream coupling chemistry during route development.
Sulfur-handle chemistry
The tert-butylsulfanyl group provides a thioether functionality that can be carried through synthesis or transformed in subsequent steps, making the compound useful where a sulfur substituent is required on the pyridine ring.
| Molecular weight | 266.40 |
|---|---|
| Empirical formula | C14H22N2OS |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(3-tert-Butylsulfanyl-pyridin-4-yl)-2,2-dimethyl-propionamide used for?
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It is used primarily as a heterocyclic building block and synthetic intermediate in pharmaceutical and medicinal-chemistry research. The protected 4-aminopyridine bearing a tert-butylthio group offers reactive handles for building more complex pyridine-based molecules. It is a research chemical and is not intended for therapeutic or consumer use.
What is the CAS number and molecular formula of N-(3-tert-Butylsulfanyl-pyridin-4-yl)-2,2-dimethyl-propionamide?
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The CAS number is 766557-59-9 and the molecular formula is C14H22N2OS (Hill notation), corresponding to a molecular weight of 266.40 g/mol.
What grade and purity does Tech Serve Solutions supply?
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We supply this compound as a research/technical-grade fine chemical for laboratory and synthesis use. We do not represent it as USP, BP or EP pharmacopoeial grade. A current specification or certificate of analysis, including the assay for the lot offered, can be provided on request so you can confirm suitability before ordering.
How should N-(3-tert-Butylsulfanyl-pyridin-4-yl)-2,2-dimethyl-propionamide be handled and stored?
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Handle as a research chemical using good laboratory practice: work in a fume hood, wear suitable gloves, eye protection and a lab coat, and avoid raising dust or aerosols. Store in a tightly closed container in a cool, dry, well-ventilated place. No GHS classification is provided in our current dataset; treat the material as potentially hazardous until you have reviewed the Safety Data Sheet, which we supply with every shipment.
How is N-(3-tert-Butylsulfanyl-pyridin-4-yl)-2,2-dimethyl-propionamide packed, shipped and exported?
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The compound is packed in appropriately sized, sealed laboratory containers with full labelling and batch identification, and is offered in research and bulk quantities. As a global supplier and exporter since 1998, Tech Serve Solutions arranges compliant international documentation and despatch, accompanied by the relevant Safety Data Sheet and certificate of analysis.
How do I request a sample or quote?
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Contact Tech Serve Solutions with the product name or CAS number 766557-59-9, the quantity required and your destination, and we will respond with availability, lead time, specification and a quotation. Samples can be discussed for evaluation, subject to availability.
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