N-(3-tert-Butylsulfanyl-pyridin-2-yl)-2,2-dimethyl-propionamide
N-(3-tert-Butylsulfanyl-pyridin-2-yl)-2,2-dimethyl-propionamide (CAS 551950-44-8) is a heterocyclic building block with the molecular formula C14H22N2OS and a molar mass of 266.40 g/mol. The molecule combines a 2-aminopyridine scaffold bearing a tert-butylsulfanyl (thioether) group at the 3-position with a pivaloyl (2,2-dimethylpropionamide) protecting group on the nitrogen. It is supplied as a research-grade reagent for chemical synthesis, principally as an intermediate in medicinal-chemistry and pyridine-based discovery programmes.
- Synonyms
- N-(3-tert-Butylsulfanyl-pyridin-2-yl)-2,2-dimethyl-propionamideN-(3-(tert-Butylthio)pyridin-2-yl)pivalamideN-[3-(tert-butylsulfanyl)pyridin-2-yl]-2,2-dimethylpropanamide2,2-Dimethyl-N-[3-(tert-butylthio)pyridin-2-yl]propanamideCAS 551950-44-8
Heterocyclic building block
Serves as a functionalised pyridine scaffold in multi-step organic synthesis, allowing further elaboration of the pyridine ring and its substituents.
Pharmaceutical and medicinal-chemistry intermediate
Used in discovery research as an advanced intermediate where a 2-aminopyridine bearing a sulfur substituent is required. Specific downstream applications depend on the synthetic route chosen by the user.
Protected 2-aminopyridine handle
The pivaloyl (2,2-dimethylpropionamide) group masks the ring-nitrogen amine and can direct ortho-functionalisation, supporting regioselective transformations on the pyridine core.
Thioether functional handle
The tert-butylsulfanyl group provides a sulfur centre that can be carried through synthesis or further modified, making the compound useful for preparing libraries of related structures.
Laboratory research and method development
Applied as a reference building block in route scouting and methodology studies at laboratory and pilot scale.
| Molecular weight | 266.40 |
|---|---|
| Empirical formula | C14H22N2OS |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(3-tert-Butylsulfanyl-pyridin-2-yl)-2,2-dimethyl-propionamide used for?
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It is used primarily as a heterocyclic building block and synthetic intermediate in chemical synthesis and medicinal-chemistry research. The molecule pairs a tert-butylsulfanyl-substituted pyridine with a pivaloyl-protected 2-amino group, making it a useful handle for regioselective further functionalisation. Specific end-uses depend on the user's synthetic route.
What is the CAS number and molecular formula of N-(3-tert-Butylsulfanyl-pyridin-2-yl)-2,2-dimethyl-propionamide?
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The CAS number is 551950-44-8. The empirical formula is C14H22N2OS (Hill notation) with a molecular weight of 266.40 g/mol.
What grade and purity does Tech Serve Solutions supply?
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We supply this compound as a research- and synthesis-grade building block. A specific assay value is not stated in the verified product data, so a certificate of analysis with the batch purity is provided on request. We do not represent this item as USP, BP or EP pharmacopoeial grade.
How should this compound be handled and stored safely?
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No GHS classification is provided in our verified data for this item, so it should be treated as a research chemical of undetermined hazard. Handle only with appropriate laboratory controls, gloves, eye protection and adequate ventilation, keep containers tightly closed, and store in a cool, dry, well-ventilated place away from incompatible materials. Refer to the accompanying safety data sheet before use.
How is N-(3-tert-Butylsulfanyl-pyridin-2-yl)-2,2-dimethyl-propionamide packed, shipped and exported?
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It is packed in suitably sealed, labelled containers sized to the order, from gram quantities for research up to larger laboratory and pilot scales. As a specialist exporter since 1998, Tech Serve Solutions arranges compliant international documentation and shipping, with packaging chosen to protect product integrity in transit.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packaging and destination, and we will confirm availability, lead time and documentation. Samples and a certificate of analysis can be provided to support evaluation.
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