Methylglyoxal 1,1-dimethyl acetal
Methylglyoxal 1,1-dimethyl acetal (CAS 6342-56-9), with the molecular formula CH3COCH(OCH3)2 and a molar mass of 118.13 g/mol, is an organic compound utilised as a building block in chemical synthesis. Its primary application involves its use in the generation of methylglyoxal through hydrolysis and in research studies investigating glycation effects on biological molecules. It is supplied by Tech Serve Solutions for laboratory and research purposes.
- IUPAC
- 1,1-Dimethoxyacetone,Pyruvaldehyde-1-dimethyl acetal,Pyruvic aldehyde dimethyl acetal
- Synonyms
- 1,1-DimethoxyacetonePyruvaldehyde-1-dimethyl acetalPyruvic aldehyde dimethyl acetal
Synthesis of Methylglyoxal
Methylglyoxal 1,1-dimethyl acetal serves as a precursor for methylglyoxal. It can be hydrolysed, typically in the presence of an acid like sulfuric acid, to yield methylglyoxal for further chemical reactions or studies.
Glycation Research
This compound has been employed to study the impact of methylglyoxal-mediated glycation. Such investigations examine how glycation affects the structure, thermal stability, and enzymatic activity of proteins like yeast enolase in biological systems.
Organic Synthesis Building Block
As an acetal, it functions as a valuable building block in organic synthesis. Its structure allows for diverse chemical transformations, contributing to the construction of more complex organic molecules.
| Molecular weight | 118.13 |
|---|---|
| Linear formula | CH3COCH(OCH3)2 |
| Assay | ≥97% |
| Boiling point | 143-147 °C(lit.) |
| Density | 0.976 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.398(lit.) |
| Application | Methylglyoxal 1,1-dimethyl acetal was used in the synthesis of methylglyoxal via hydrolysis in the presence of H2SO41. It was used to investigate the effects of methylglyoxal-mediated glycation on the structure, thermal stability and enzyme activity of yeast enolase in vivo2. |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 26 °C / 78.8 °F |
| Transport (UN / ADR) | UN 1224C 3 / PGIII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methylglyoxal 1,1-dimethyl acetal used for?
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Methylglyoxal 1,1-dimethyl acetal is used as a precursor in the synthesis of methylglyoxal and in research to investigate the effects of methylglyoxal-mediated glycation on biological molecules.
What is the CAS number and formula for Methylglyoxal 1,1-dimethyl acetal?
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The CAS number is 6342-56-9, and the linear formula is CH3COCH(OCH3)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methylglyoxal 1,1-dimethyl acetal with an assay of ≥97%. This product is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Methylglyoxal 1,1-dimethyl acetal be handled safely?
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This compound is flammable and causes skin and eye irritation. Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, in a well-ventilated area. Refer to the Safety Data Sheet for full details.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions adheres to strict international regulations for packing, shipping, and exporting chemicals, including UN 1224C 3 / PGIII classification for transport.
How can I request a quote or sample?
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To request a quote or a sample of Methylglyoxal 1,1-dimethyl acetal, please contact our sales team through the TSS website or direct inquiry channels.
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