Methyl thioglycolate
Methyl thioglycolate (CAS: 2365-48-2), with the linear formula HSCH₂CO₂CH₃ and a molecular weight of 106.14, is a sulfur-containing organic compound. It is primarily employed as a versatile building block in chemical synthesis. Its reactive thiol and ester functionalities make it valuable in various organic transformations. This compound is supplied by Tech Serve Solutions for research and industrial applications requiring precise chemical intermediates.
- IUPAC
- Methyl mercaptoacetate
- Synonyms
- Methyl mercaptoacetate

Chemical Synthesis Intermediate
Methyl thioglycolate serves as a key intermediate in the synthesis of more complex organic molecules. Its thiol group can participate in nucleophilic reactions, while the ester moiety can undergo hydrolysis or transesterification.
Building Block for Heterocycles
The compound is utilized in the construction of sulfur-containing heterocyclic compounds, which are prevalent in pharmaceuticals and materials science. Its structure lends itself to cyclization reactions.
Reagent in Organic Chemistry
It functions as a reagent in various organic transformations, including addition reactions and the formation of thioethers. Its applications span academic research and industrial process development.
| Molecular weight | 106.14 |
|---|---|
| Linear formula | HSCH2CO2CH3 |
| Assay | 95% |
| Boiling point | 42-43 °C/10 mmHg(lit.) |
| Density | 1.187 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.466(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 56 °C / 132.8 °F |
| Transport (UN / ADR) | UN 1992 3/PG 3 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-20/22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl thioglycolate used for?
+
Methyl thioglycolate is primarily used as a versatile building block and intermediate in chemical synthesis, particularly for constructing sulfur-containing organic molecules and heterocycles.
What is the CAS number and formula for Methyl thioglycolate?
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The CAS number for Methyl thioglycolate is 2365-48-2, and its linear formula is HSCH₂CO₂CH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl thioglycolate with an assay of 95%. We do not represent this product as USP, BP, or EP grade.
What are the main safety hazards associated with Methyl thioglycolate?
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Methyl thioglycolate is a flammable liquid and vapor (H226). It is toxic if swallowed (H301), causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Inhalation may also be harmful (H332).
How is Methyl thioglycolate packed and shipped by TSS?
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Methyl thioglycolate is packed according to international shipping regulations for hazardous materials and is exported globally by Tech Serve Solutions.
How can I request a sample or quote for Methyl thioglycolate?
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To request a sample or obtain a quote for Methyl thioglycolate, please contact our sales team through the TSS website.
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