Methyl diphenylphosphinite
Methyl diphenylphosphinite (CAS: 4020-99-9) is an organophosphorus compound with the linear formula (C6H5)2POCH3 and a molecular weight of 216.22 g/mol. This chemical serves as a valuable ligand and catalyst precursor in various organic synthesis applications, particularly within hydroformylation and annulation reactions. Its phosphinite structure makes it suitable for complex catalytic transformations in both academic research and industrial chemical synthesis.
- IUPAC
- Diphenylmethoxyphosphine,Methoxydiphenylphosphine,NSC 171167
- Synonyms
- DiphenylmethoxyphosphineMethoxydiphenylphosphineNSC 171167
Catalyst for Hydroformylation Reactions
Methyl diphenylphosphinite acts as a catalyst or ligand in rhodium-catalysed hydroformylation of bishomoallylic alcohols and in the preparation of gamma-lactones via branched-regioselective hydroformylation.
Ligand in Nickel-Catalyzed Cyanation
It is employed as a ligand in nickel-catalysed hydrocyanation reactions, facilitating the addition of hydrogen cyanide to unsaturated organic compounds.
Catalysis in Annulation Reactions
The compound serves as a catalyst in annulation reactions, enabling the formation of cyclic structures through the joining of molecules.
Desymmetrization of Alkenyl Carbinols
Used as a catalyst for the hydroformylative desymmetrization of bisalkenyl carbinols and bishomoallylic carbinols, a key step in stereoselective synthesis.
| Molecular weight | 216.22 |
|---|---|
| Linear formula | (C6H5)2POCH3 |
| Assay | 97% |
| Boiling point | 149 °C/6 mmHg(lit.) |
| Density | 1.078 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.604(lit.) |
| Storage temperature | 2-8°C |
| Application | Ased as:• Catalyst for hydroformylative desymmetrization of bisalkenyl carbinols and bishomoallylic carbinols1• Ligand in rhodium-catalyzed hydroformylation of bishomoallylic alcohols2• Calatyst in preparation of γ-lactones via branched-regioselective hydroformylation reactions3• Ligand for nickel-catalyzed hydrocyanation reactions4• Catalyst in annulation reactions5 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl diphenylphosphinite used for?
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Methyl diphenylphosphinite is used as a ligand and catalyst in various organic synthesis reactions, including hydroformylation, annulation, and cyanation.
What is the CAS number and formula for Methyl diphenylphosphinite?
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The CAS number is 4020-99-9 and the linear formula is (C6H5)2POCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl diphenylphosphinite with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for Methyl diphenylphosphinite?
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This compound is a Warning substance (GHS07) and causes skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Always use appropriate personal protective equipment, including eyeshields and gloves, and ensure adequate ventilation. Refer to the Safety Data Sheet for full details.
How is Methyl diphenylphosphinite packed, shipped, and exported?
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Methyl diphenylphosphinite is packed and shipped according to relevant regulations for hazardous materials (UN 2810 6.1 / PGIII). As a global supplier, Tech Serve Solutions expertly handles international export requirements.
How can I request a sample or quote for Methyl diphenylphosphinite?
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To request a sample or a quotation for Methyl diphenylphosphinite, please contact our sales team through the website or by phone, providing your specific requirements.
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