Methyl (R)-(+)-3-Boc-2,2-dimethyl-4-oxazolidinecarboxylate
Methyl (R)-(+)-3-Boc-2,2-dimethyl-4-oxazolidinecarboxylate (CAS: 95715-86-9), a chiral oxazolidinone derivative, has the molecular formula C12H21NO5 and a molecular weight of 259.30 g/mol. This compound is a valuable building block in asymmetric synthesis, facilitating the stereoselective construction of complex molecules. Its utility extends to chemical synthesis and as a chiral auxiliary, aiding in the control of stereochemistry during various chemical transformations.
- IUPAC
- Methyl (R)-(+)-3-(tert-butoxycarbonyl)-2,2-dimethyl-4-oxazolidinecarboxylate
- Synonyms
- C12H21NO5Methyl (R)-(+)-3-(tert-butoxycarbonyl)-2,2-dimethyl-4-oxazolidinecarboxylate
Chiral Auxiliary in Asymmetric Synthesis
This compound serves as a critical chiral auxiliary, enabling the stereoselective addition of nucleophiles to electrophilic centres. Its rigid structure and defined stereochemistry allow for high levels of enantioselectivity in various synthetic strategies.
Building Block for Pharmaceutical Intermediates
The molecule's distinct chiral framework makes it suitable for the synthesis of complex pharmaceutical intermediates. It can be incorporated into drug discovery programs requiring specific stereochemical configurations for biological activity.
Research and Development in Organic Chemistry
Used in academic and industrial research laboratories, this oxazolidinone derivative is a key reagent for exploring new synthetic methodologies and developing novel chiral compounds. Its well-defined properties support reliable and reproducible experimental outcomes.
| Molecular weight | 259.30 |
|---|---|
| Empirical formula | C12H21NO5 |
| Assay | 98% |
| Boiling point | 89 °C/0.8 mmHg(lit.) |
| Density | 1.082 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.444(lit.) |
| Optical activity | [α]20/D +54°, c = 1.3 in chloroform |
| Optical purity | ee: 99% (HPLC) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 93 °C / 199.4 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl (R)-(+)-3-Boc-2,2-dimethyl-4-oxazolidinecarboxylate used for?
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Methyl (R)-(+)-3-Boc-2,2-dimethyl-4-oxazolidinecarboxylate is primarily used as a chiral auxiliary in asymmetric synthesis and as a building block in chemical synthesis, particularly for pharmaceutical intermediates.
What are the CAS number and molecular formula?
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The CAS number is 95715-86-9, and the molecular formula is C12H21NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 98%. This is a technical/research grade material, and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia standard.
How should this chemical be handled safely?
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This compound is classified as a Warning with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Recommended personal protective equipment includes eyeshields, gloves, and appropriate respiratory protection such as a multi-purpose combination respirator cartridge (US) or type ABEK (EN14387) respirator filter. Ensure adequate ventilation.
Is this product available for export?
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Yes, Tech Serve Solutions specialises in global supply and export of fine chemicals, including Methyl (R)-(+)-3-Boc-2,2-dimethyl-4-oxazolidinecarboxylate.
How can I request a sample or quote?
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To request a sample or a quote, please use the enquiry form on our website or contact our sales department directly with your specific requirements.
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