Methyl (R)-(+)-3-hydroxy-5-oxo-1-cyclopentene-1-heptanoate
Methyl (R)-(+)-3-hydroxy-5-oxo-1-cyclopentene-1-heptanoate (CAS 41138-61-8) is an organic building block with the empirical formula C13H20O4 and a molecular weight of 240.30 g/mol. This chiral compound, specified at 97% purity, is primarily utilised in asymmetric synthesis. Its key application lies in the preparation of mexiprostil, a prostaglandin E1 derivative known for its gastric acid inhibition and mucosal protective properties.
Synthesis of Mexiprostil
This compound serves as a crucial intermediate in the synthesis of mexiprostil, a synthetic analogue of prostaglandin E1. Mexiprostil is recognised for its therapeutic effects in reducing gastric acid secretion and protecting the gastric lining.
Chiral Building Block
As a chiral molecule with defined stereochemistry, it is valuable in asymmetric synthesis for constructing complex molecules where specific enantiomers are required. Its structure lends itself to the introduction of chirality in pharmaceutical intermediates.
Prostaglandin Analogue Synthesis
The structural features of Methyl (R)-(+)-3-hydroxy-5-oxo-1-cyclopentene-1-heptanoate make it a suitable precursor for synthesising various prostaglandin analogues, which have diverse physiological roles and therapeutic applications.
| Molecular weight | 240.30 |
|---|---|
| Empirical formula | C13H20O4 |
| Assay | 97% |
| Optical activity | [α]23/D +10°, c = 1 in chloroform |
| Optical purity | ee: 97% (HPLC) |
| Application | Used in the synthesis of mexiprostil, a PGE1 derivative that inhibits gastric acid secretions and protects the gastric mucosa.1 |
| Melting point | 59-63 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl (R)-(+)-3-hydroxy-5-oxo-1-cyclopentene-1-heptanoate used for?
+
This compound is primarily used in the synthesis of mexiprostil, a PGE1 derivative that inhibits gastric acid secretions and protects the gastric mucosa. It also functions as a chiral building block in asymmetric synthesis.
What are the CAS number and formula for Methyl (R)-(+)-3-hydroxy-5-oxo-1-cyclopentene-1-heptanoate?
+
The CAS number is 41138-61-8, and the empirical formula is C13H20O4.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this chemical with an assay of 97% and an optical purity of ee: 97% (HPLC). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for this chemical?
+
Appropriate personal protective equipment, including eyeshields and gloves, should be used. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Handle with care, as indicated by its WGK Germany classification of 3.
How is this chemical packed, shipped, and exported?
+
Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific packing, shipping, and export details are available upon request.
How can I request a sample or obtain a quotation?
+
To request a sample or a quotation for Methyl (R)-(+)-3-hydroxy-5-oxo-1-cyclopentene-1-heptanoate, please contact our sales team through the website or by phone.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis