Methyl (R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carboxylate
Methyl (R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carboxylate (CAS 52373-72-5) is a chiral building block with the molecular formula C7H12O4 and a molecular weight of 160.17 g/mol. This ester is valuable in asymmetric synthesis due to its defined stereochemistry. It serves as a key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical and fine chemical research and development. Its protected glycerol structure offers versatile synthetic utility.
- IUPAC
- α,β-Isopropylidene-D-glyceric acid methyl ester,Methyl α,β-isopropylidene-D-glycerate,Methyl 2,3-O-isopropylidene-D-glycerate
- Synonyms
- 52373-72-5C7H12O4α,β-Isopropylidene-D-glyceric acid methyl esterMethyl α,β-isopropylidene-D-glycerateMethyl 2,3-O-isopropylidene-D-glycerate
Chiral Building Block
Utilised in the construction of enantiomerically pure compounds, this molecule provides a stereodefined fragment for complex syntheses. Its protected diol functionality allows for regioselective transformations in organic synthesis.
Asymmetric Synthesis
Serves as a starting material or intermediate in stereoselective reactions, facilitating the creation of chiral molecules. It is instrumental in developing new synthetic routes for pharmaceuticals and agrochemicals.
Pharmaceutical Intermediates
Acts as a precursor in the synthesis of active pharmaceutical ingredients (APIs) where specific stereochemistry is critical for biological activity. Its structural features are amenable to various functional group manipulations.
Organic Synthesis Research
A valuable reagent for academic and industrial research laboratories exploring novel synthetic methodologies and complex molecule construction. Its availability with high enantiomeric purity supports reliable research outcomes.
| Molecular weight | 160.17 |
|---|---|
| Empirical formula | C7H12O4 |
| Assay | 98% |
| Boiling point | 70-75 °C/10 mmHg(lit.) |
| Density | 1.106 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.426(lit.) |
| Optical activity | [α]20/D +8.5°, c = 1.5 in acetone |
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 75 °C / 167 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl (R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carboxylate used for?
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Methyl (R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carboxylate is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical research.
What is the CAS number and formula for this compound?
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The CAS number is 52373-72-5, and the empirical formula is C7H12O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl (R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carboxylate with an assay of 98%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.
What are the safety and handling considerations for this chemical?
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This compound is combustible, with a flash point of 75°C (167°F). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection (e.g., multi-purpose combination respirator cartridge or ABEK filter), should be used when handling. It has a WGK rating of 3 in Germany, indicating a significant hazard to water.
How is this product packed, shipped, and exported?
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As a global supplier and exporter, Tech Serve Solutions ensures products are appropriately packed for safe transit and export in compliance with international regulations. Specific packaging details are available upon request.
How can I request a sample or quote for this chemical?
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To request a sample or a quote, please contact our sales department via the website or direct email, providing your contact details and the required quantity.
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