2-Fluoroanisole
2-Fluoroanisole (CAS 321-28-8, FC6H4OCH3) is a fluorinated aromatic compound with a molecular weight of 126.13 g/mol. As a versatile building block, it is primarily utilised in organic synthesis for the introduction of fluorinated phenyl moieties. Its properties make it suitable for research and development applications within the chemical and pharmaceutical industries.

Organic Synthesis Intermediate
2-Fluoroanisole serves as a key intermediate in the synthesis of more complex organic molecules. Its fluorinated aromatic structure is valuable for creating novel compounds with specific electronic or biological properties.
Pharmaceutical Research
The compound is employed in medicinal chemistry research to develop new drug candidates. Fluorine substitution can significantly impact a molecule's metabolic stability, lipophilicity, and binding affinity.
Materials Science
It can be utilised in the development of specialty materials where fluorinated aromatic units are required to impart desired characteristics such as thermal stability or altered electronic properties.
| Molecular weight | 126.13 |
|---|---|
| Linear formula | FC6H4OCH3 |
| Assay | 98% |
| Grade | purum |
| Boiling point | 154-155 °C(lit.) |
| Density | 1.124 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.494(lit.) |
| Melting point | −39 °C(lit.) |
| Flash point | 53 °C / 127 °F |
|---|---|
| Transport (UN / ADR) | UN 1993 3/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Risk statements (R) | 10 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoroanisole used for?
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2-Fluoroanisole is primarily used as a building block in organic synthesis, particularly in pharmaceutical research and materials science, to introduce fluorinated phenyl groups into larger molecules.
What are the CAS number and formula for 2-Fluoroanisole?
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The CAS number for 2-Fluoroanisole is 321-28-8, and its chemical formula is FC6H4OCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoroanisole with a purity of 98% (purum grade). This product is intended for research and laboratory use and is not represented as USP/BP/EP.
How should 2-Fluoroanisole be handled safely?
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2-Fluoroanisole is a flammable liquid and vapour. It can cause skin and eye irritation. Handle in a well-ventilated area, away from heat and open flames. Refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.
Is 2-Fluoroanisole a controlled substance?
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Based on the provided data, 2-Fluoroanisole is not indicated as a controlled substance.
How is 2-Fluoroanisole packed and shipped?
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2-Fluoroanisole is typically packed in appropriate containers for safe transport and is exported globally by Tech Serve Solutions according to relevant shipping regulations.
How can I request a quote or sample of 2-Fluoroanisole?
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To request a quote or a sample of 2-Fluoroanisole, please contact our sales team via the website or phone, providing your specific requirements.
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