2-Fluoro-β-nitrostyrene
2-Fluoro-β-nitrostyrene (CAS: 399-25-7, Formula: C8H6FNO2, Molar Mass: 167.14 g/mol) is a fluorinated organic building block. This compound serves as a valuable intermediate in chemical synthesis, particularly in the development of complex organic molecules. Its structure, featuring both a fluorine atom and a nitro group conjugated with an alkene, offers unique reactivity for various synthetic transformations.
- IUPAC
- 1-(2-Fluorophenyl)-2-nitroethylene

Organic Synthesis Intermediate
2-Fluoro-β-nitrostyrene is utilized as a key intermediate in the synthesis of more complex organic compounds. The presence of the electron-withdrawing nitro group and the fluorine atom activates the double bond for various nucleophilic addition reactions.
Pharmaceutical Research
This compound can be employed in the research and development of novel pharmaceutical agents. Fluorinated organic molecules are often explored for their potential to enhance drug properties such as metabolic stability and lipophilicity.
Material Science
As a building block, 2-Fluoro-β-nitrostyrene may find applications in the synthesis of specialized polymers or functional materials where its specific chemical properties are advantageous.
| Molecular weight | 167.14 |
|---|---|
| Empirical formula | C8H6FNO2 |
| Assay | ≥98.0% |
| Melting point | 55-57 °C |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-β-nitrostyrene used for?
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2-Fluoro-β-nitrostyrene is primarily used as an intermediate in organic synthesis and in pharmaceutical research.
What is the CAS number and formula for 2-Fluoro-β-nitrostyrene?
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The CAS number is 399-25-7 and the molecular formula is C8H6FNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-β-nitrostyrene with an assay of ≥98.0%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for 2-Fluoro-β-nitrostyrene?
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This compound is classified as harmful if swallowed and causes skin and eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment including a dust mask (N95), eyeshields, face shields, and gloves should be used. Handle in a well-ventilated area and avoid breathing dust.
How is 2-Fluoro-β-nitrostyrene packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports fine chemicals in compliance with all relevant international regulations, ensuring safe and secure delivery worldwide.
How can I request a sample or a quote for 2-Fluoro-β-nitrostyrene?
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To request a sample or obtain a quotation, please contact our sales department via the website or by phone, referencing the product name or CAS number.
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