Methyl 3,4-O-isopropylidene-L-threonate
Methyl 3,4-O-isopropylidene-L-threonate (CAS: 92973-40-5) is a valuable carbohydrate derivative with the molecular formula C8H14O5. This compound serves as a key intermediate in organic synthesis, notably in the total synthesis of complex natural products. Its defined stereochemistry makes it particularly useful for building chiral molecules. Supplied by Tech Serve Solutions, it meets high standards for research and development applications.
- IUPAC
- (αR,4S)-2,2-Dimethyl-α-hydroxy-1,3-dioxolane-4-acetic acid methyl ester,3,4-O-Isopropylidene-L-threonic acid methyl ester
- Synonyms
- 3,4-O-Isopropylidene-L-threonic acid methyl ester(αR,4S)-2,2-Dimethyl-α-hydroxy-1,3-dioxolane-4-acetic acid methyl ester
Dihydrofuran Substrate Synthesis
Methyl 3,4-O-isopropylidene-L-threonate is utilised in the preparation of dihydrofuran substrates. This is a critical step in the total synthesis of the natural product (-)-echinosporin, showcasing its utility in complex molecule construction.
Chiral Building Block
As a carbohydrate derivative, this compound possesses defined stereocentres. It functions as a versatile chiral building block, enabling the stereoselective synthesis of complex organic molecules and pharmaceuticals.
Organic Synthesis Intermediate
This chemical acts as a reliable intermediate in various organic synthesis pathways. Its structure allows for diverse chemical transformations, facilitating the development of novel compounds in academic and industrial research.
| Molecular weight | 190.19 |
|---|---|
| Empirical formula | C8H14O5 |
| Assay | ≥90% (sum of enantiomers, GC) |
| Boiling point | 125 °C/12 mmHg(lit.) |
| Density | 1.175 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.446(lit.)n20/D 1.446 |
| Optical activity | [α]20/D +17.5±1°, c = 1% in chloroform |
| Application | Used to prepare a dihydrofuran substrate in the total synthesis of (-)-echinosporin.1 |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 99 °C / 210.2 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 3,4-O-isopropylidene-L-threonate used for?
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It is used to prepare a dihydrofuran substrate in the total synthesis of (-)-echinosporin and serves as a chiral building block in organic synthesis.
What is the CAS number and formula for Methyl 3,4-O-isopropylidene-L-threonate?
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The CAS number is 92973-40-5, and the empirical formula (Hill notation) is C8H14O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 3,4-O-isopropylidene-L-threonate with an assay of ≥90% (sum of enantiomers, GC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Methyl 3,4-O-isopropylidene-L-threonate be handled safely?
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Safe handling requires appropriate personal protective equipment, including eyeshields and gloves. For specific hazards and protection, refer to the safety data sheet. The flash point is 99 °C (210.2 °F).
Can Tech Serve Solutions export Methyl 3,4-O-isopropylidene-L-threonate?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Methyl 3,4-O-isopropylidene-L-threonate.
How can I request a quote or sample for this chemical?
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Please contact our sales team directly via the website or by phone to request a quotation or a sample of Methyl 3,4-O-isopropylidene-L-threonate.
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