Methoxypolyethylene glycol maleimide
Methoxypolyethylene glycol maleimide (CAS 99126-64-4) is a functionalised polymer featuring a terminal maleimide group and a methoxy-capped polyethylene glycol (PEG) chain. This structure allows for selective conjugation to thiol-containing molecules via Michael addition. Its applications span materials science, polymer chemistry, and bioconjugation, enabling the modification of surfaces, nanoparticles, and biomolecules for advanced research and development purposes.
- IUPAC
- MeO-PEG-Mal,PEG-maleimide,mono-Methyl polyethylene glycol 2-maleimidoethyl ether
- Synonyms
- MeO-PEG-MalPEG-maleimidemono-Methyl polyethylene glycol 2-maleimidoethyl ether
Bioconjugation
The maleimide moiety readily reacts with sulfhydryl groups on peptides, proteins, and antibodies, facilitating the creation of antibody-drug conjugates (ADCs) or labelled biomolecules for diagnostics and therapeutics.
Materials Surface Modification
This reagent can be used to functionalise surfaces, such as nanoparticles or sensor arrays, with PEG chains. This imparts desirable properties like increased solubility, reduced non-specific binding, and tailored surface chemistry.
Polymer Synthesis and Modification
It serves as a building block or modifying agent in polymer science. The PEG chain provides hydrophilicity and biocompatibility, while the maleimide group offers a reactive handle for further polymerisation or cross-linking.
| Storage temperature | −20°C |
|---|
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Mol Wt | PEG average Mn 750 |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methoxypolyethylene glycol maleimide used for?
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Methoxypolyethylene glycol maleimide (CAS 99126-64-4) is primarily used in bioconjugation for modifying proteins and peptides, in materials science for surface functionalisation, and in polymer chemistry for creating functionalised polymers.
What is the CAS number and formula for Methoxypolyethylene glycol maleimide?
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The CAS number is 99126-64-4. The chemical formula is not specified in the provided data, but it is a methoxy-capped polyethylene glycol chain terminated with a maleimide group.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methoxypolyethylene glycol maleimide with a PEG average molecular weight of Mn 750. This product is intended for research and laboratory use. TSS does not represent this product as USP, BP, or EP grade.
How should Methoxypolyethylene glycol maleimide be handled and stored?
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This compound requires storage at −20°C. When handling, appropriate personal protective equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter should be used due to potential hazards.
Is Methoxypolyethylene glycol maleimide a controlled substance?
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The provided data does not indicate that Methoxypolyethylene glycol maleimide (CAS 99126-64-4) is a controlled substance.
How is this chemical shipped or exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, capable of shipping and exporting Methoxypolyethylene glycol maleimide worldwide, adhering to all necessary regulations.
How can I request a sample or quote for Methoxypolyethylene glycol maleimide?
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To request a sample or quote, please contact the Tech Serve Solutions sales team through our official website or designated sales channels, providing the product name and CAS number (99126-64-4).
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