Methoxypolyethylene glycol amine
Methoxypolyethylene glycol amine (CAS: 80506-64-5) is a functionalised polymer featuring a primary amine group at one end and a methoxy group at the other, linked by a polyethylene glycol chain. This structure imparts water solubility and reactive amine functionality. It is widely employed as a versatile building block in materials science, polymer chemistry, and bioconjugation for modifying surfaces, creating drug delivery systems, and synthesising novel polymers.
- IUPAC
- O-(2-Aminoethyl)-O′-methylpolyethylene glycol,Aminopolyethylene glycol monomethyl ether,Methoxypolyoxyethylene amine
- Synonyms
- O-(2-Aminoethyl)-O′-methylpolyethylene glycolAminopolyethylene glycol monomethyl etherMethoxypolyoxyethylene amine
Bioconjugation and Surface Modification
This amine-terminated PEG derivative can be used to introduce polyethylene glycol chains onto biomolecules or surfaces. This process enhances solubility, reduces immunogenicity, and provides a platform for further functionalization in areas like diagnostics and targeted drug delivery.
Polymer Synthesis
It serves as a monomer or chain extender in the synthesis of advanced polymers, including block copolymers and graft copolymers. The amine group allows for incorporation into polymer backbones or side chains via reactions with electrophilic groups.
Drug Delivery Systems
Methoxypolyethylene glycol amine is utilised in the preparation of nanocarriers, hydrogels, and other drug delivery vehicles. Its PEGylation properties improve drug circulation time and enable targeted delivery strategies.
Materials Science Research
Researchers use this compound to create functionalised materials with tailored properties. Applications include the development of advanced coatings, sensors, and biocompatible materials for biomedical devices.
| Linear formula | H2NCH2CH2(OCH2CH2)nOCH3 |
|---|---|
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Extent Of Labeling | ≥0.17 mmol/g NH2 loading |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methoxypolyethylene glycol amine used for?
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Methoxypolyethylene glycol amine is used in bioconjugation, surface modification, polymer synthesis, drug delivery systems, and general materials science research. It acts as a building block for creating functionalised polymers and modifying surfaces and biomolecules.
What is the CAS number and formula for Methoxypolyethylene glycol amine?
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The CAS number is 80506-64-5. The linear formula is H₂NCH₂CH₂(OCH₂CH₂)nOCH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methoxypolyethylene glycol amine with a minimum amine loading of 0.17 mmol/g. This product is suitable for research and industrial applications. It is not supplied as USP, BP, or EP grade.
What are the safety and handling recommendations for Methoxypolyethylene glycol amine?
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It is classified under WGK Germany 3. Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. Store at 2-8°C.
How is Methoxypolyethylene glycol amine supplied and exported?
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Tech Serve Solutions, a specialist global supplier and exporter, packages Methoxypolyethylene glycol amine according to industry best practices to ensure product integrity during transit and storage. We export worldwide.
How can I request a sample or quote for Methoxypolyethylene glycol amine?
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Please contact our sales team via the website or by phone to request a sample or a quotation for Methoxypolyethylene glycol amine. We are happy to assist with your specific requirements.
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