α-Chlorophenylacetyl chloride
α-Chlorophenylacetyl chloride (CAS 2912-62-1) is an organic compound with the linear formula C<sub>6</sub>H<sub>5</sub>CHClCOCl and a molecular weight of 189.04 g/mol. This acid halide is a key intermediate in organic synthesis, primarily utilised as a building block. It serves as a precursor in the preparation of various organic compounds, including pharmaceuticals and agrochemicals, owing to its reactive acyl chloride group and chlorophenyl moiety. It is supplied at a purity of 90%.
Synthesis of α-Chlorophenylacetic Acid
α-Chlorophenylacetyl chloride is employed as a direct precursor in the synthesis of α-chlorophenylacetic acid (CPAA). This transformation is a fundamental step in accessing derivatives with potential pharmaceutical applications.
Preparation of Chloro-Telechelic Macroinitiators
This compound has been utilised in the preparation of specific chloro-telechelic macroinitiators. These macroinitiators are important in polymer chemistry for controlled polymerisation processes.
Organic Synthesis Building Block
As a versatile organic building block, α-Chlorophenylacetyl chloride participates in various acylation reactions. Its structure allows for the introduction of the chlorophenylacetyl group into diverse molecular frameworks.
| Molecular weight | 189.04 |
|---|---|
| Linear formula | C6H5CHClCOCl |
| Assay | 90% |
| Boiling point | 120 °C/23 mmHg(lit.) |
| Density | 1.196 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.544(lit.) |
| Application | α-Chlorophenylacetyl chloride was used in the synthesis of α-chlorophenylacetic acid (CPAA)1. It was also used to prepare chloro-telechelic macroinitiators2. |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 51 °C / 123.8 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-14-34-36/37 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is α-Chlorophenylacetyl chloride used for?
+
α-Chlorophenylacetyl chloride is primarily used as an intermediate in organic synthesis, including the preparation of α-chlorophenylacetic acid and chloro-telechelic macroinitiators.
What is the CAS number and formula for α-Chlorophenylacetyl chloride?
+
The CAS number is 2912-62-1 and the linear formula is C<sub>6</sub>H<sub>5</sub>CHClCOCl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies α-Chlorophenylacetyl chloride with an assay of 90%. This product is not intended for USP, BP, EP, or other pharmacopoeia grades.
How should α-Chlorophenylacetyl chloride be handled safely?
+
α-Chlorophenylacetyl chloride is a corrosive and flammable liquid that reacts violently with water. Handle with extreme care in a well-ventilated area, wearing appropriate personal protective equipment including gloves, goggles, a face shield, and respiratory protection. Avoid contact with water and incompatible materials. Refer to the Safety Data Sheet for comprehensive guidance.
How is this chemical exported and shipped?
+
Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. This product is shipped according to international regulations for hazardous materials, including UN 2920, Hazard Class 3 (Flammable Liquid) and 8 (Corrosive), Packing Group II.
How can I request a sample or quote for α-Chlorophenylacetyl chloride?
+
To request a sample or a quotation, please contact our sales team through the dedicated portal on the Tech Serve Solutions website, providing your specific requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis