α-Cyano-4-hydroxycinnamic acid
α-Cyano-4-hydroxycinnamic acid (CAS 28166-41-8), molecular formula HOC6H4CH=C(CN)CO2H, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.
- IUPAC
- α-CCA,α-CHCA,α-Cyano,4-HCCA,ACCA,alpha-Cyano-4-hydroxycinnamic acid

| Molecular weight | 189.17 |
|---|---|
| Linear formula | HOC6H4CH=C(CN)CO2H |
| Assay | 97% |
| Solubility | methanol: soluble50 mg/mL, clear to slightly hazy, light yellow to yellow |
| Storage temperature | 2-8°C |
| Application | α-Cyano-4-hydroxycinnamic acid(CHC) was used as a matrix for peptides1 and nucleotides2 in mass spectroscopic analysis. It was used in encapsulation of CHC into NaY zeolite3. It was used as matrix to investigate the activity of the paclitaxel derivatives using several well-established in vitro angiogenesis assays4. |
| Melting point | 245-250 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Analyte Suitability | glycanspeptidesproteins |
|---|
Documentation
Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is α-Cyano-4-hydroxycinnamic acid?
+
α-Cyano-4-hydroxycinnamic acid (CAS 28166-41-8), molecular formula HOC6H4CH=C(CN)CO2H, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to USP, BP and EP standards.
What grades of α-Cyano-4-hydroxycinnamic acid does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies α-Cyano-4-hydroxycinnamic acid in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.
What is the CAS number and molecular formula of α-Cyano-4-hydroxycinnamic acid?
+
α-Cyano-4-hydroxycinnamic acid has CAS number 28166-41-8 and molecular formula HOC6H4CH=C(CN)CO2H. Full specifications appear in the table above and in the Certificate of Analysis.
What is the typical minimum order quantity and lead time for α-Cyano-4-hydroxycinnamic acid?
+
Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.
Do you provide a Certificate of Analysis (CoA) with each shipment?
+
Yes. Every batch of α-Cyano-4-hydroxycinnamic acid ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.
How should α-Cyano-4-hydroxycinnamic acid be stored?
+
Store α-Cyano-4-hydroxycinnamic acid in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.
What is α-Cyano-4-hydroxycinnamic acid used for?
+
α-Cyano-4-hydroxycinnamic acid is used in chemical synthesis applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.
How do I request a quote for α-Cyano-4-hydroxycinnamic acid?
+
Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis



