trans-3,4-Difluorocinnamic acid
trans-3,4-Difluorocinnamic acid (CAS: 112897-97-9) is a fluorinated organic building block with the molecular formula F₂C₆H₃CH=CHCO₂H and a molecular weight of 184.14 g/mol. This compound serves as a key intermediate in organic synthesis. Its structure, featuring a difluorinated phenyl ring and a trans-substituted alkene, makes it valuable for introducing specific functionalities into more complex molecules. It is typically supplied at 95% purity.
- Synonyms
- F2C6H3CH=CHCO2H
Synthesis of Bromovinylbenzene Derivatives
trans-3,4-Difluorocinnamic acid is utilized in the preparation of halogenated aromatic compounds. Specifically, it has been employed in the synthesis of (E)-4-(2-bromovinyl)-1,2-difluorobenzene, a useful intermediate in further synthetic transformations.
Fluorinated Organic Building Block
As a difluorinated cinnamic acid derivative, this compound acts as a versatile building block in medicinal chemistry and materials science. The fluorine atoms can influence lipophilicity, metabolic stability, and binding interactions in target molecules.
Intermediate for Fine Chemical Synthesis
The presence of the carboxylic acid group, the alkene, and the difluorinated phenyl ring offers multiple reaction sites for constructing complex organic structures, making it a valuable reagent in the multi-step synthesis of fine chemicals.
| Molecular weight | 184.14 |
|---|---|
| Linear formula | F2C6H3CH=CHCO2H |
| Assay | 95% |
| Application | trans-3,4-Difluorocinnamic acid has been used in the synthesis of (E)-4-(2-bromovinyl)-1,2-difluorobenzene1. |
| Melting point | 194-196 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is trans-3,4-Difluorocinnamic acid used for?
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trans-3,4-Difluorocinnamic acid is used as a building block in organic synthesis, particularly for preparing halogenated aromatic compounds like (E)-4-(2-bromovinyl)-1,2-difluorobenzene and as an intermediate in the synthesis of fine chemicals.
What are the CAS number and formula for trans-3,4-Difluorocinnamic acid?
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The CAS number is 112897-97-9, and its linear formula is F₂C₆H₃CH=CHCO₂H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies trans-3,4-Difluorocinnamic acid with an assay of 95%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should trans-3,4-Difluorocinnamic acid be handled safely?
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Handling requires appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. This compound is a skin, eye, and respiratory irritant (H315, H319, H335).
Is trans-3,4-Difluorocinnamic acid a controlled substance?
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The provided data does not indicate that trans-3,4-Difluorocinnamic acid is a controlled substance.
How is trans-3,4-Difluorocinnamic acid shipped and exported?
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As a specialist global supplier and exporter, Tech Serve Solutions handles the packaging, shipping, and export of fine chemicals like trans-3,4-Difluorocinnamic acid in compliance with all relevant regulations.
How can I request a sample or quote for trans-3,4-Difluorocinnamic acid?
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To request a sample or a quote, please contact our sales department through the website or by phone. Our team will be pleased to assist you.
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