McN-A-343
McN-A-343 (CAS: 55-45-8), with the molecular formula C14H18Cl2N2O2 and a molecular weight of 317.21 g/mol, is a research chemical primarily utilised in scientific studies. It functions as a cholinergic agonist, playing a role in research related to cell signaling and neuroscience. Its application in understanding neurotransmission makes it a valuable tool for scientists investigating neuronal pathways and functions.
- IUPAC
- (4-Hydroxy-2-butynyl)-1-trimethylammonium-3-chlorocarbanilate chloride,4-[N-(3-Chlorophenyl)carbamoyloxy]-2-butynyltrimethylammonium chloride

Neuroscience Research
McN-A-343 serves as a cholinergic agonist, enabling researchers to study the mechanisms of neurotransmission and the role of the cholinergic system in various neurological processes. Its use facilitates investigations into receptor function and signaling pathways within the nervous system.
Cell Signaling Studies
As a bioactive small molecule, McN-A-343 is employed to probe cellular signaling cascades, particularly those involving cholinergic receptors. This allows for a deeper understanding of cellular responses to specific stimuli in biological research.
Pharmacological Investigations
The compound's defined chemical structure and agonist activity make it a useful tool for in-vitro pharmacological investigations. Scientists can use it to characterise receptor subtypes and explore potential therapeutic targets in research settings.
| Molecular weight | 317.21 |
|---|---|
| Empirical formula | C14H18Cl2N2O2 |
| Assay | ≥98% (TLC) |
| Form | powder |
| Colour | off-white |
| Solubility | H2O: solubleethanol: soluble |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)rat ... Chrm1(25229) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is McN-A-343 used for?
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McN-A-343 is used in scientific research, primarily as a cholinergic agonist for studies in neuroscience, cell signaling, and pharmacological investigations.
What is the CAS number and molecular formula for McN-A-343?
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The CAS number for McN-A-343 is 55-45-8, and its molecular formula is C14H18Cl2N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies McN-A-343 with an assay of ≥98% (TLC). TSS does not represent this product as USP, BP, or EP grade.
What are the key safety considerations when handling McN-A-343?
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Handling McN-A-343 requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the safety data sheet for comprehensive handling information. Its WGK Germany rating is 3.
How is McN-A-343 packaged, shipped, and exported?
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McN-A-343 is carefully packaged to ensure stability and integrity during transit. As a global supplier, Tech Serve Solutions has extensive experience in exporting chemicals worldwide, adhering to all relevant shipping regulations.
How can I request a sample or quote for McN-A-343?
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To request a sample or a quote for McN-A-343, please contact our sales department through the website or by email, providing your specific requirements.
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