Luzindole

CAS 117946-91-5C19H20N2OBiochemicals & Reagents

Luzindole (CAS: 117946-91-5), with the molecular formula C19H20N2O and a molecular weight of 292.37, is a valuable biochemical reagent. It functions as a selective antagonist for melatonin receptors MTNR1A and MTNR1B. This compound is widely utilised in biochemical research for studying cellular signalling pathways, particularly those involving melatonin and its receptors, in areas such as neuroscience and cell biology. Luzindole is supplied with a minimum assay of 90%.

IUPAC: N-Acetyl-2-benzyltryptamine,N-[2-[2-(Phenylmethyl)-1H-indol-3-yl]ethyl]acetamide

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Luzindole (C19H20N2O) — chemical structure, CAS 117946-91-5; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBiochemicals and ReagentsCell BiologyGPCR ModulatorsGPCR ProteinsModulators and AntibodiesMelatoninsNeurobiologyNeurosciencePharmacologicals

01 /Applications

Melatonin Receptor Antagonism

Luzindole acts as a selective antagonist for melatonin receptors MTNR1A and MTNR1B. This makes it a crucial tool for researchers investigating the physiological roles of melatonin signalling in various biological systems.

Neuroscience Research

Due to its interaction with melatonin receptors, which are prevalent in the brain, Luzindole is employed in neuroscience to explore the mechanisms of circadian rhythms, sleep regulation, and other neural processes influenced by melatonin.

Cell Biology Studies

As a bioactive small molecule, Luzindole aids in studying cellular responses and signalling pathways mediated by melatonin receptors. Its application spans various cell types where these receptors are expressed.

GPCR Modulator Research

Luzindole serves as a research tool for understanding G-protein coupled receptor (GPCR) function, specifically targeting the melatonin receptors. This helps in characterising GPCR activity and developing new pharmacological probes.

02 /Properties

Molecular weight	292.37
Empirical formula	C19H20N2O
Assay	≥90%
Solubility	DMSO: soluble5 mg/mL
Storage temperature	−20°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

117946-91-5

MDL number

MFCD00672498

PubChem substance

24896315

05 /Additional specifications

Gene Information	human ... MTNR1A(4543), MTNR1B(4544)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Luzindole used for?

Luzindole is used as a selective antagonist for melatonin receptors MTNR1A and MTNR1B, making it valuable in research for studying cell signalling, neuroscience, and neurobiology, particularly concerning circadian rhythms and sleep.

What are the CAS number and molecular formula for Luzindole?

The CAS number for Luzindole is 117946-91-5, and its molecular formula is C19H20N2O.

What grade and purity does Tech Serve Solutions supply for Luzindole?

Tech Serve Solutions supplies Luzindole with a minimum assay of 90%. This product is intended for research purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.

How should Luzindole be handled and stored?

When handling Luzindole, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The recommended storage temperature is -20°C.

Is Luzindole a controlled substance?

The provided data does not indicate that Luzindole is a controlled substance.

How is Luzindole packed, shipped, and exported?

Tech Serve Solutions adheres to stringent quality control measures for packing, shipping, and exporting chemicals like Luzindole, ensuring product integrity and compliance with international regulations.

How can I request a sample or quote for Luzindole?

To request a sample or quote for Luzindole, please contact the Tech Serve Solutions sales team through our website or by phone, providing your contact details and the quantity required.